B-cell lymphoma causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Adnan Ezici, M.D[2]
Overview
The exact cause of B-cell lymphoma has not been identified. However, there are several factors associated with the development of B-cell lymphoma including infections, environmental factors, immunodeficiency states, and autoimmune diseases.
Causes
The exact cause of B-cell lymphoma has not been identified. However, there are several factors associated with the development of B-cell lymphoma including:[1][2]
- Infections such as Epstein Barr virus (EBV), HTLV-1, HHV8, Hepatitis C virus, Helicobacter pylori
- Environmental factors such as drugs (phenytoin, digoxin, TNF antagonist), pesticides, solvents, organic chemicals, radiation exposure, etc.
- Immunodeficiency states such as severe combined immunodeficiency, Wiskott-Aldrich syndrome, AIDS, and immunosuppressive therapy
- Autoimmune diseases such as rheumatoid arthritis, Sjögren's syndrome, celiac disease, and Hashimoto's thyroiditis