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Otosclerosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] CSN, M.D. Christina Ninan, M.D.


Synonyms and keywords: Otospongiosis

Overview

Otosclerosis is a word derived from the Greek word "sklērós" meaning hardening and oto meaning ear. Otosclerosis is a disorder in which the footplate of the stapes is replaced by an abnormal bone, thereby affecting sound transmission to the inner ear at the level of the oval window.[1] osseous dyscrasia limited to the temporal bone that results in slow, progressive conductive hearing loss(emedicine) (CT) scanning of the temporal bone can often demonstrate foci of demineralization in the otic capsule in cases of cochlear otosclerosis

Historical perspective

  • 1704:Antonio Maria Valsalva identified fixation of stapes as a cause of hearing loss[2]
  • 1841:Toyn bee stated, "osseous ankylosis of the stapes to the fenestra ovalis as one of the causes of deafness".[3]
  • 1876:Johannes Kessel described stapes surgery as the treatment.[4]
  • 1930-1950: Used Julius Lempert’s single-stage fenestration of stapes as treatment.[5]
  • 1956:John Shea modernized stapedectomy.[6]

Classification

Embryology

Pathophysiology

Etiology

Pathophysiology

SAMPLE

  • USMLE STEP 1
  • USMLE STEP 2
    • USMLE STEP 2 CK
    • USMLE STEP 2 CS
  • USMLE STEP 3
    • USMLE STEP 3 MCQ
    • USMLE STEP 3 CCS92F + atrial fibrillation + numbness/tingling of her right leg; where is the stroke lesion?
  1. left or right side of the brain?
à answer = left (contralateral).
  1. medial or lateral cerebral hemisphere?
àanswer = medial (homunculus for lower limb is

medial, upper limb and face are lateral).

  1. anterior or posterior to the central sulcus?
ànswer = posterior (primary sensory cortexis posterior; primary motor is anterior))
  1. Rajput MSA, Arain AA, Rajput AA, Adeel M, Suahil A, Awan MS (2020). "Otosclerosis: Experience With Stapes Surgery". Cureus. 12 (5): e7927. doi:10.7759/cureus.7927. PMC 7265776 Check |pmc= value (help). PMID 32499972 Check |pmid= value (help).
  2. Makarem AO, Hoang TA, Lo WW, Linthicum FH, Fayad JN (2010). "Cavitating otosclerosis: clinical, radiologic, and histopathologic correlations". Otol Neurotol. 31 (3): 381–4. doi:10.1097/MAO.0b013e3181d275e8. PMC 2880664. PMID 20195188.
  3. Nazarian R, McElveen JT, Eshraghi AA (2018). "History of Otosclerosis and Stapes Surgery". Otolaryngol Clin North Am. 51 (2): 275–290. doi:10.1016/j.otc.2017.11.003. PMID 29502722.
  4. Wielgosz R, Mroczkowski E (2008). "[History of endaural surgery]". Otolaryngol Pol. 62 (3): 348–50. doi:10.1016/S0030-6657(08)70269-5. PMID 18652164.
  5. Pietruski J (1998). "[Juliusz Lempert (1890-1959): the author of the fenestration technique]". Otolaryngol Pol. 52 (3): 341–6. PMID 9760779.
  6. Cheng HCS, Agrawal SK, Parnes LS (2018). "Stapedectomy Versus Stapedotomy". Otolaryngol Clin North Am. 51 (2): 375–392. doi:10.1016/j.otc.2017.11.008. PMID 29397948.