C4 glomerulopathy natural history

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C4 glomerulopathy Microchapters

Complement Mediated Glomerular Disorders Main Page

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Differentiating C4 glomerulopathy from other Diseases

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Ali Poyan Mehr, M.D. [2]; Associate Editor(s)-in-Chief: Olufunmilola Olubukola M.D.[3]

Overview

If left untreated, C4 glomerulopathy may progress to develop renal failure.

Natural History, Complications, and Prognosis

Natural History

The symptoms of C4 glomerulopathy usually develop during or after the second decade of life and start with symptoms such as proteinuria, hematuria, edema, renal insufficiency hypocomplementemia, and hypertension.

Complications

Common complications of C4 glomerulopathy include:

  • Renal failure

Prognosis

Depending on the extent of the disease at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor.

References

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