Pediatrics Related Questions

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Pediatrics Related Questions

Are children with congenital heart diseases at increased risk of COVID-19?

  • A study published in the Journal of the American Heart Association investigated the effects of COVID-17 in the pediatric and adolescent population with congenital heart disease(CHD).[1] The results found that patients with CHD are more susceptible to being infected by COVID-19 and may in fact have worse outcomes and complications due to the disease. This is as a result of their already disturbed physiologic states as well as other co-morbidities associated with congenital heart diseases.[1] For these individuals, primary prevention and infection control processes are especially crucial.

Are children with underlying conditions at increased risk of hospitalization?

  • Almost all children infected with COVID-19 have excellent outcomes. However of those hospitalized due to the disease, the majority are children under the age of 1,[2][3] and those with underlying conditions. The most commonly reported conditions include:[2] [4]
    • pulmonary diseases i.e; asthma
    • congenital heart disease and other cardiovascular conditions
    • Immunosuppression due to cancer or any of its treatment therapies, high dose of glucocorticoids, e.t.c

Is there and an association between KAWASAKI disease and COVID-19?

  • Kawasaki disease, also known as lymph node syndrome, mucocutaneous node disease, infantile polyarteritis, and Kawasaki syndrome, is a poorly understood self-limited vasculitis that affects many organs, including the skin, mucous membranes, lymph nodes, blood vessel walls, and the heart.[5] The emergence of COVID-19 has seen new presentations of known medical conditions for the first time.[6] Numerous reports have shown a spike in new/concurrent cases of Kawasaki disease in COVID-19 positive patients. Information regarding the novel COVID-19 is still being gathered and although an exact association hasn't been established between Kawasaki disease and COVID-19, more research and investigations are still being conducted.[7]

Is Multi-system Inflammatory Syndrome in Children (MIS-C) fatal? What precautions can be taken to avoid it?

Should routinely-recommended Hepatitis A and B vaccines continue to be administered to children?

Should vaccinations for HBV exposed infants be continued during the COVID 19 pandemic?

Sources

  1. 1.0 1.1 Alsaied T, Aboulhosn JA, Cotts TB, Daniels CJ, Etheridge SP, Feltes TF, Gurvitz MZ, Lewin MB, Oster ME, Saidi A (June 2020). "Coronavirus Disease 2019 (COVID-19) Pandemic Implications in Pediatric and Adult Congenital Heart Disease". J Am Heart Assoc. 9 (12): e017224. doi:10.1161/JAHA.120.017224. PMID 32441586 Check |pmid= value (help).
  2. 2.0 2.1 "Coronavirus Disease 2019 in Children - United States, February 12-April 2, 2020". MMWR Morb. Mortal. Wkly. Rep. 69 (14): 422–426. April 2020. doi:10.15585/mmwr.mm6914e4. PMC 7147903 Check |pmc= value (help). PMID 32271728 Check |pmid= value (help).
  3. "Coronavirus Disease 2019 (COVID-19) Treatment Guidelines".
  4. "UpToDate".
  5. "Kawasaki disease overview - wikidoc".
  6. "Association Between COVID-19 and Kawasaki Disease: Vigilance Required From Otolaryngologists - Henya Sandhaus, Dana Crosby, Arun Sharma, Stacie R. Gregory,".
  7. "Trending Clinical Topic: Kawasaki Disease and COVID-19".