Wild-type (senile) amyloidosis pathophysiology
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
Pathophysiology
Pathogenesis
- Wild-type (senile) amyloidosis is a type of systemic amyloidosis.
- The culprit protein responsible for the disease is transthyretin (TTR) and it is deposited in the non-mutated form, hence the name "Wild-type".
- The normal TTR protein compared with the mutated form is less likely to get deposited and to cause a pathology