Hypoglycemia surgery

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Surgical removal of the overactive part of the pancreas is curative with minimal risk when hyperinsulinism is focal or due to a benign insulin-producing tumor of the pancreas. When congenital hyperinsulinism is diffuse and refractory to medications, near-total pancreatectomy may be the treatment of last resort, but in this condition is less consistently effective and fraught with more complications.

Surgery

  • Surgical removal of the insulinoma is the treatment of choice. [8]
  • Enucleation of the insulinoma
  • Partial distal pancreatectomy
  • Distal subtotal pancreatectomy is recommended for patients with insulinoma related to MEN1.37
  • Recurrences were more common in the patients with MEN1;  [8].
  • Hepatic resection is indicated for the treatment of metastatic liver disease if general condition is good. Resection should be considered only for patients with a limited number of hepatic metastases.

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