Hypoglycemia surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Surgical removal of the overactive part of the pancreas is curative with minimal risk when hyperinsulinism is focal or due to a benign insulin-producing tumor of the pancreas. When congenital hyperinsulinism is diffuse and refractory to medications, near-total pancreatectomy may be the treatment of last resort, but in this condition is less consistently effective and fraught with more complications.
Surgery
- Surgical removal of the insulinoma is the treatment of choice. [8]
- Enucleation of the insulinoma
- Partial distal pancreatectomy
- Distal subtotal pancreatectomy is recommended for patients with insulinoma related to MEN1.37
- Recurrences were more common in the patients with MEN1; [8].
- Hepatic resection is indicated for the treatment of metastatic liver disease if general condition is good. Resection should be considered only for patients with a limited number of hepatic metastases.