Sandbox Turky3

Aspergillosis

Invasive pulmonary aspergillosis

• Preferred regimen: Voriconazole (6 mg/kg IV every 12 h for 1 day, followed by 4 mg/kg IV every 12 h; oral dosage is 200 mg every 12 h)
• Alternative regimen: Liposomal amphotericin B(L-AMB) 3–5 mg/kg/day IV OR Amphotericin B lipid complex (ABLC) 5 mg/ kg/day IVOR Caspofungin (70 mg day 1 IV and 50 mg/day IV thereafter) OR Micafungin (IV 100–150 mg/day; dose not established ), Posaconazole (200 mg QID initially, then 400 mg BID PO after stabilization of disease ),Itraconazole (dosage depends upon formulation)