Sandbox subdural empyema
Antimicrobial Regimen – Empiric Therapy
Infants < 1 month
Infants 1–3 months
Infants > 3 months or adults < 55 years (immunocompetent)
Adults ≥ 55 years, alcoholics, or with debilitating illness
Hospital-acquired, post-neurosurgery, or post-traumatic meningitis; impaired cell-mediated immunity, neutropenia
- Ciprofloxacin 400 mg IV q8h
- Piperacillin-Tazobacbam 3.375g IV q4h AND
- Tobramycin 3–5 mg/kg/day IV q8h
- Imipenem 0.5 g IV q6h OR Meropenem 1 g IV q8h OR Cefepime 2 g IV q12h OR Ceftazidime 2 g IV q8h