WBR0367

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Author [[PageAuthor::[User:Gonzalo Romero]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Pharmacology
Sub Category SubCategory::Cardiology, SubCategory::General Principles
Prompt [[Prompt::A 25-year-old man presents to the emergency department for altered mental status. He was brought in by his mother who found him lying on his bedroom floor. She reports that her son is a very healthy person with no significant past medical history. He was only recently diagnosed with performance anxiety that was interfering with his daily functioning at his new job as a financial advisor. The mother also notes that her son has been very anxious for the past week because of an upcoming project presentation. On admission, the patient's blood pressure is 80/55 mm Hg, heart rate is 42/min, and temperature is 36.7 ᵒC (98 ᵒF). The patient is not responsive, but opens his eyes to painful stimuli. An ECG tracing is obtained and shown below. Which of the following medications is the most appropriate choice for the acute treatment of this patient?

File:WBR0366.jpg]]

Answer A AnswerA::Cyproheptadine
Answer A Explanation [[AnswerAExp::Cyproheptadine is used to treat the management of moderate to severe cases of serotonin syndrome. This excess of serotonin can be caused by SSRIs excess, MAO Inhibitors intoxication and carcinoid tumor.]]
Answer B AnswerB::Glucagon
Answer B Explanation [[AnswerBExp::Glucagon is used to reverse the intoxication of Betablockers.]]
Answer C AnswerC::Flumazenil
Answer C Explanation [[AnswerCExp::Flumazenil reverses the effects of benzodiazepines.]]
Answer D AnswerD::Naloxone
Answer D Explanation [[AnswerDExp::Naloxone is used to reverse acute intoxications with Opioids.]]
Answer E AnswerE::Sodium bicarbonate
Answer E Explanation [[AnswerEExp::Sodium bicarbonate alkalinizes the urine allowing the elimination of acidic substances in the urine by inhibiting the reabsorption. It can be used in cases of Salicylates and TCAs intoxication.]]
Right Answer RightAnswer::B
Explanation [[Explanation::

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Approved Approved::Yes
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