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11 June 2026
- 12:2412:24, 11 June 2026 Garadacimab-gxii (hist | edit) [17,277 bytes] Anum Ijaz (talk | contribs) (Created page with "{{DrugProjectFormSinglePage |authorTag={{AIJ}} |aOrAn=an |drugClass=activated Factor XII (FXIIa) inhibitor (monoclonal antibody) |indicationType=prophylaxis |indication=preventing attacks of hereditary angioedema (HAE) in adult and pediatric patients aged 12 years and older. |adverseReactions=are nasopharyngitis and abdominal pain (incidence ≥ 7%). |blackBoxWarningTitle='''<span style="color:#FF0000;">TITLE</span>''' |blackBoxWarningBody=''<span style="color:#F...")
10 June 2026
- 00:3500:35, 10 June 2026 Mechanical circulatory support in cardiogenic shock (hist | edit) [42,188 bytes] Nehal Eid (talk | contribs) (Created page with "### Mechanical Circulatory Support in Cardiogenic Shock **NOTOC** {{Mechanical circulatory support in cardiogenic shock}} {{CMG}}; {{AE}} {{Nehal}} ==Overview== Cardiogenic shock (CS) is a clinical syndrome of inadequate tissue perfusion due to the inability of the heart to pump sufficient blood to meet metabolic demands. Despite advances in reperfusion therapy and critical care, CS remains the leading cause of in-hospital death among patients with acute m...")
- 00:1800:18, 10 June 2026 Emergent PCI protocols and door-to-balloon time management (hist | edit) [39,839 bytes] Nehal Eid (talk | contribs) (Created page with " {{CMG}} {{AE}} {{Nehal}} NOTOC {{SI}} ==Overview== Emergent percutaneous coronary intervention (PCI) is the preferred reperfusion strategy for patients presenting with ST-segment elevation myocardial infarction (STEMI). The concept of '''door-to-balloon (D2B) time''' refers to the interval from a patient's arrival at the hospital to the inflation of the first balloon (or activation of the first device) to restore coronary blood flow. Timely primary PCI (PPCI...")
7 June 2026
- 21:4221:42, 7 June 2026 Taletrectinib (hist | edit) [32,641 bytes] Anum Ijaz (talk | contribs) (Created page with "{{DrugProjectFormSinglePage |authorTag={{AIJ}} |aOrAn=a |drugClass=kinase inhibitor |indicationType=treatment |indication=adult patients with locally advanced or metastatic ROS1-positive non-small cell lung cancer (NSCLC). |adverseReactions=diarrhea, nausea, vomiting, dizziness, rash, constipation, and fatigue (>20%). |blackBoxWarningTitle='''<span style="color:#FF0000;">TITLE</span>''' |blackBoxWarningBody=''<span style="color:#FF0000;">Condition Name:</...")
6 June 2026
- 22:1522:15, 6 June 2026 GC rich repressor elements (hist | edit) [757 bytes] Marshallsumter (talk | contribs) (Created page with "==GC rich repressor element== GC rich repressor element Down regulation of smooth muscle myosin heavy chain (SM MHC) expression in cultured smooth muscle cells is associated with progressive methylation of a GC rich repressor element (GCGGGA) within the SM MHC promoter.[1] ==References== 1. Julian M Rozenberg, Daniel B Tesfu, Srilaxmi Musunuri, Joan M Taylor & Christopher P Mack (December 2014). DNA methylation...")
- 19:4019:40, 6 June 2026 Α-Palindromic binding proteins (hist | edit) [1,001 bytes] Marshallsumter (talk | contribs) (Created page with "α-Palindromic binding proteins The palindromic sequence here designated Order 377 (r) TGCGCATGCGCA (c) ACGCGTACGCGT (1) (i) TGCGCATGCGCA (ci) ACGCGTACGCGT (1) also called the α-palindromic binding protein (α-PAL) that binds the nuclear respiratory factor 1 (NRF-1)[1] does not occur on either side of A1BG nor any other IDC. Number 377 Order 377 alpha palindromic binding protein (r) TGCGCATGCGCA = (i)...")
5 June 2026
- 12:5312:53, 5 June 2026 Clesrovimab-cfor (hist | edit) [21,676 bytes] Anum Ijaz (talk | contribs) (Created page with "{{DrugProjectFormSinglePage |authorTag={{AIJ}} |aOrAn=a |drugClass=respiratory syncytial virus (RSV) F protein-directed fusion inhibitor |indicationType=prevention |indication=RSV lower respiratory tract disease in neonates and infants who are born during or entering their first RSV season. |adverseReactions=injection-site erythema (3.8%), injection-site swelling (2.7%) and rash (2.3%). |blackBoxWarningTitle='''<span style="color:#FF0000;">TITLE</...")
3 June 2026
- 13:1313:13, 3 June 2026 Acoltremon (hist | edit) [10,394 bytes] Anum Ijaz (talk | contribs) (Created page with "{{DrugProjectFormSinglePage |authorTag={{AIJ}} |aOrAn=a |drugClass=TRPM8 thermoreceptor agonist |indicationType=treatment |indication=the signs and symptoms of dry eye disease. |adverseReactions=instillation site pain (50%). |blackBoxWarningTitle='''<span style="color:#FF0000;">TITLE</span>''' |blackBoxWarningBody=''<span style="color:#FF0000;">Condition Name:</span>'' (Content) |fdaLIADAdult=====FDA-labeled Indications==== * TRYPTYR is indicated for the...")
2 June 2026
- 14:2714:27, 2 June 2026 Telisotuzumab vedotin-tllv (hist | edit) [28,383 bytes] Anum Ijaz (talk | contribs) (Created page with "{{DrugProjectFormSinglePage |authorTag={{AIJ}} |aOrAn=a |drugClass=a c-Met-directed antibody and microtubule inhibitor conjugate |indicationType=treatment |indication=adult patients with locally advanced or metastatic non-squamous non-small cell lung cancer (NSCLC) with high c-Met protein overexpression [≥50% of tumor cells with strong (3+) staining], as determined by an FDA-approved test, who have received a prior systemic therapy. |adverseReactions=were perip...")
25 May 2026
- 13:3713:37, 25 May 2026 Avutometinib potassium and Defactinib hydrochloride (hist | edit) [35,103 bytes] Anum Ijaz (talk | contribs) (Created page with "{{DrugProjectFormSinglePage |authorTag={{AIJ}} |genericName=Avutometinib and Defactinib |aOrAn=a |drugClass=combination of avutometinib and defactinib, each kinase inhibitors, |indicationType=treatment |indication=adult patients with KRAS-mutated recurrent low-grade serous ovarian cancer (LGSOC) who have received prior systemic therapy. |adverseReactions=laboratory abnormalities, were increased creatine phosphokinase, nausea, fatigue, increased aspartate aminotransferase...")
- 11:5511:55, 25 May 2026 Nipocalimab-aahu (hist | edit) [30,203 bytes] Anum Ijaz (talk | contribs) (Created page with "{{DrugProjectFormSinglePage |authorTag={{AIJ}} |genericName=Nipocalimab |aOrAn=a |drugClass=neonatal Fc receptor blocker |indicationType=treatment |indication=generalized myasthenia gravis (gMG) in adult and pediatric patients 12 years of age and older who are anti-acetylcholine receptor (AChR) or anti-muscle-specific tyrosine kinase (MuSK) antibody positive. |adverseReactions=respiratory tract infections, peripheral edema, and muscle spasms ( in patients with gMG treate...")
24 May 2026
- 02:3402:34, 24 May 2026 Penpulimab (hist | edit) [42,564 bytes] Anum Ijaz (talk | contribs) (Created page with "{{DrugProjectFormSinglePage |authorTag={{AIJ}} |genericName=Penpulimab |aOrAn=a |drugClass=programmed death receptor-1 (PD-1)-blocking antibody |indicationType=treatment |indication=* In combination with either cisplatin or carboplatin and gemcitabine for the first-line treatment of adults with recurrent or metastatic non-keratinizing nasopharyngeal carcinoma (NPC). * As a single agent for the treatment of adults with metastatic non-keratinizing NPC with disease progres...")
23 May 2026
- 22:1122:11, 23 May 2026 Atrasentan (hist | edit) [23,500 bytes] Anum Ijaz (talk | contribs) (Created page with "{{DrugProjectFormSinglePage |authorTag={{AIJ}} |genericName=Atrasentan |aOrAn=an |drugClass=endothelin receptor antagonist |indicationType=treatment |indication=in adults with primary immunoglobulin A nephropathy (IgAN) at risk of rapid disease progression, generally a urine protein-to-creatinine ratio (UPCR) ≥ 1.5 g/g. |hasBlackBoxWarning=Yes |adverseReactions=peripheral edema and anemia (incidence >5%). |blackBoxWarningTitle='''<span style="color:#FF0000;"> EMBRYO-FE...")
22 May 2026
- 01:5301:53, 22 May 2026 Fitusiran (hist | edit) [36,754 bytes] Anum Ijaz (talk | contribs) (Created page with "{{DrugProjectFormSinglePage |authorTag={{AIJ}} |aOrAn=an |drugClass=antithrombin-directed small interfering ribonucleic acid |indicationType=prophylaxis |indication=to prevent or reduce the frequency of bleeding episodes in adult and pediatric patients aged 12 years and older with hemophilia A or B with or without factor VIII or IX inhibitors. |adverseReactions=viral infection, nasopharyngitis, and bacterial infection. |blackBoxWarningTitle='''<span style="co...")
21 May 2026
- 14:0614:06, 21 May 2026 Gepotidacin (hist | edit) [42,400 bytes] Anum Ijaz (talk | contribs) (Created page with "{{DrugProjectFormSinglePage |aOrAn=a |drugClass=triazaacenaphthylene bacterial type II topoisomerase inhibitor |indicationType=treatment |indication=of the following infections caused by susceptible microorganisms: * Uncomplicated urinary tract infections (uUTI) in female adult and pediatric patients 12 years of age and older weighing at least 40 kilograms (kg). * Uncomplicated Urogenital Gonorrhea: The recommended dosage of BLUJEPA is 3,000 mg (four 750 mg tablets)...") originally created as "Gepoticadin"
20 May 2026
- 18:1818:18, 20 May 2026 Vimseltinib (hist | edit) [25,025 bytes] Anum Ijaz (talk | contribs) (Created page with "{{DrugProjectFormSinglePage |aOrAn=a |drugClass=kinase inhibitor |indicationType=treatment |indication=adult patients with symptomatic tenosynovial giant cell tumor (TGCT) for which surgical resection will potentially cause worsening functional limitation or severe morbidity. |adverseReactions=laboratory abnormalities are increased AST, periorbital edema, fatigue, rash, increased cholesterol, peripheral edema, face edema, decreased neutr...")
18 May 2026
- 01:2201:22, 18 May 2026 Mirdametinib (hist | edit) [19,194 bytes] Anum Ijaz (talk | contribs) (Created page with "{{DrugProjectFormSinglePage |authorTag={{AIJ}} |aOrAn=a |drugClass=kinase inhibitor |indicationType=treatment |indication=adult and pediatric patients 2 years of age and older with neurofibromatosis type 1 (NF1) who have symptomatic plexiform neurofibromas (PN) not amenable to complete resection. |adverseReactions=Ocular Toxicity, Left Ventricular Dysfunction, Dermatologic Adverse Reactions, and Embryo-Fetal Toxicity. |blackBoxWarningTitle='''<spa...")