Esophageal stricture causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]


Overview

Common causes of esophageal stricture include gastroesophageal reflux disease and caustic ingestions.

Causes

Life-threatening Causes

  • Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. There are no life-threatening causes of esophageal stricture, however complications resulting from untreated esophageal stricture is common.

Common Causes

Esophageal stricture may be caused by:[1]

Less Common Causes

Less common causes of esophageal stricture include:

Causes by Organ System

Cardiovascular No underlying causes
Chemical/Poisoning Caustic ingestion
Dental No underlying causes
Dermatologic Dyskeratosis congenita (DC), epidermolysis bullosa dystrophica
Drug Side Effect Drug-induced stricture:[10]
Ear Nose Throat No underlying causes
Endocrine Zollinger-Ellison syndrome,
Environmental No underlying causes
Gastroenterologic Gastroesophageal reflux disease, Eosinophilic esophagitis, Esophageal diverticula, Zollinger-Ellison syndrome, Systemic sclerosis
Genetic No underlying causes
Hematologic No underlying causes
Iatrogenic Previous surgery on the esophagus, Radiation therapy for thoracic or head and neck tumors, Esophageal sclerotherapy,Tracheoesophageal fistula repair, Nasogastric tube placement, Heller myotomy for achalasia
Infectious Disease Infectious esophagitis
Musculoskeletal/Orthopedic No underlying causes
Neurologic No underlying causes
Nutritional/Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic No underlying causes
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Mediastinal fibrosis due to tuberclosis or idiopathic fibrosing mediastinitis
Renal/Electrolyte No underlying causes
Rheumatology/Immunology/Allergy Systemic sclerosis
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous No underlying causes

Causes in Alphabetical Order

List the causes of the disease in alphabetical order.

  • Caustic ingestions
  • Drug-induced stricture
  • Dyskeratosis congenita (DC)
  • Eosinophilic esophagitis
  • Esophageal diverticula
  • Esophageal sclerotherapy
  • Gastroesophageal reflux disease
  • Increased level of gastric acid exposure to esophageal tissue
  • Infectious esophagitis
  • Mediastinal fibrosis due to tuberclosis or idiopathic fibrosing mediastinitis
  • Radiation therapy for thoracic or head and neck tumors
  • Rare dermatologic diseases (eg, epidermolysis bullosa dystrophica)
  • Tracheoesophageal fistula repair and esophageal stricture at the anastomosis

References

  1. Csendes A, Braghetto I (1992). "Surgical management of esophageal strictures". Hepatogastroenterology. 39 (6): 502–10. PMID 1483661.
  2. Marks RD, Richter JE (1993). "Peptic strictures of the esophagus". Am. J. Gastroenterol. 88 (8): 1160–73. PMID 8338082.
  3. Wasserman RL, Ginsburg CM (1985). "Caustic substance injuries". J. Pediatr. 107 (2): 169–74. PMID 4020540.
  4. Coia LR, Myerson RJ, Tepper JE (1995). "Late effects of radiation therapy on the gastrointestinal tract". Int. J. Radiat. Oncol. Biol. Phys. 31 (5): 1213–36. doi:10.1016/0360-3016(94)00419-L. PMID 7713784.
  5. Guynn TP, Eckhauser FE, Knol JA, Raper SE, Mulholland MW, Nostrant TT, Elta GH, Barnett JL (1991). "Injection sclerotherapy-induced esophageal strictures. Risk factors and prognosis". Am Surg. 57 (9): 567–71, discussion 571–2. PMID 1928999.
  6. Furuta, Glenn T.; Ingelfinger, Julie R.; Katzka, David A. (2015). "Eosinophilic Esophagitis". New England Journal of Medicine. 373 (17): 1640–1648. doi:10.1056/NEJMra1502863. ISSN 0028-4793.
  7. Jonassaint NL, Guo N, Califano JA, Montgomery EA, Armanios M (2013). "The gastrointestinal manifestations of telomere-mediated disease". Aging Cell. 12 (2): 319–23. doi:10.1111/acel.12041. PMC 3602337. PMID 23279657.
  8. Guerra-Leal JD, Meester I, Cantu-Gonzalez JR, Ornelas-Cortinas G, Montemayor-Martinez A, Salas-Alanis JC (2016). "The Importance of Esophagography in Patients With Recessive Dystrophic Epidermolysis Bullosa". AJR Am J Roentgenol: 1–4. doi:10.2214/AJR.16.16115. PMID 27384758.
  9. Goenka MK, Gupta NM, Kochhar R, Rungta U, Vaiphei K, Nagi B, Suri S (1995). "Mediastinal fibrosis: an unusual cause of esophageal stricture". J. Clin. Gastroenterol. 20 (4): 331–3. PMID 7665827.
  10. 10.0 10.1 Bonavina L, DeMeester TR, McChesney L, Schwizer W, Albertucci M, Bailey RT (1987). "Drug-induced esophageal strictures". Ann Surg. 206 (2): 173–83. PMC 1493104. PMID 3606243.
  11. 11.0 11.1 Kikendall JW, Friedman AC, Oyewole MA, Fleischer D, Johnson LF (1983). "Pill-induced esophageal injury. Case reports and review of the medical literature". Dig. Dis. Sci. 28 (2): 174–82. PMID 6825537.
  12. Wilcox CM (2013). "Overview of infectious esophagitis". Gastroenterol Hepatol (N Y). 9 (8): 517–9. PMC 3980995. PMID 24719600.
  13. Lakoma A, Fallon SC, Mathur S, Kim ES (2013). "Use of Mitomycin C for Refractory Esophageal Stricture following Tracheoesophageal Fistula Repair". European J Pediatr Surg Rep. 1 (1): 24–6. doi:10.1055/s-0033-1341418. PMC 4335951. PMID 25755944.
  14. Smith, C. Daniel (2015). "Esophageal Strictures and Diverticula". Surgical Clinics of North America. 95 (3): 669–681. doi:10.1016/j.suc.2015.02.017. ISSN 0039-6109.
  15. Ebert, Ellen C. (2008). "Esophageal disease in progressive systemic sclerosis". Current Treatment Options in Gastroenterology. 11 (1): 64–69. doi:10.1007/s11938-008-0008-8. ISSN 1092-8472.
  16. 16.0 16.1 Luedtke, Pia; Levine, Marc S.; Rubesin, Stephen E.; Weinstein, Donald S.; Laufer, Igor (2003). "Radiologic Diagnosis of Benign Esophageal Strictures: A Pattern Approach". RadioGraphics. 23 (4): 897–909. doi:10.1148/rg.234025717. ISSN 0271-5333.
  17. Ferguson MK (1991). "Achalasia: current evaluation and therapy". Ann. Thorac. Surg. 52 (2): 336–42. PMID 1863166.

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