Hereditary nonpolyposis colorectal cancer laboratory tests
Hereditary Nonpolyposis Colorectal Cancer Microchapters |
Differentiating Hereditary Nonpolyposis Colorectal Cancer from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
The laboratory findings associated with hereditary nonpolyposis colorectal cancer are mainly related with the evaluation of genetic mutations; such as the germline testing for a deleterious mutation in the MMR (MLH1, MSH2, MSH6, and PMS2) or EPCAM gene. Other laboratory findings include: GCBC, FOBT, serum CEA, CA 19-9 concentration and CA 125, serum iron concentrations, serum vitamin B12 and folate concentrations, liver function tests, and pulmonary function tests.