Patent ductus arteriosus physical examination: Difference between revisions

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===Extremities===
===Extremities===
* Eisenmenger syndrome ([[cyanosis]] and [[clubbing]], and preferential cyanosis more pronounced in lower extremities than upper) may develop in case of reversal of shunt.
* [[Cyanosis]]
* [[Clubbing]]
 
* Differential cyanosis i.e. [[cyanosis]] is more pronounced in lower extremities compared to upper.This is so because the ductus originates distal to the [[left subclavian artery]]. The left subclavian artery mainly supplies the upper extremities which escapes the [[shunting]] of [[blood]].


==References==
==References==

Revision as of 18:46, 22 January 2013

Patent Ductus Arteriosus Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Priyamvada Singh, M.B.B.S. [2], Cafer Zorkun, M.D., Ph.D. [3], Assistant Editor-In-Chief: Kristin Feeney, B.S. [4]

Overview

The physical examination varies depending on the size of patent ductus arteriosus and the amount of blood mixing across the ductus.

Physical Examination

Vital Signs

Pulse

  • Brisk upstroke pulse: Bounding arterial pulses are present due to the continuous runoff of blood from the aorta into the pulmonary artery during diastole.

Blood Pressure

Heart

Small PDA

  • Pulmonary to systemic flow ratio <1.5 to 1
  • Normal precordial activity
  • Murmur may be present. Its nature may be different for neonates and older patient. This is so because of the relative difference in pulmonary and systemic vascular resistance in them.
  • Features of machinery murmur are:
    • Best heard in the left infraclavicular region.
    • The murmur may be 3/6 or less.
    • The intensity is maximal immediately before and after the second heart sound (S2).
    • Not vary with changing postures.

Moderate PDA

  • Pulmonary to systemic flow ratio between 1.5 and 2.2 to 1
  • As a result of the runoff from the aorta, there are bounding pulses, and the pulse pressure widens.
  • A continuous thrill may be present in the first or second left intercostal space.
  • Displaced apex (indicating left ventricular overload)
  • Continuous murmur (may be grade 2,3 and occasionally 4)
  • The features of murmur are very similar to that seen with small ducts, however, they are louder than that associated with small PDA

Large PDA

  • Pulmonary to systemic flow ratio >2.2 to 1
  • Dynamic left ventricular impulse
  • Left ventricular thrill
  • S1 is normal, S2 may be split with an accentuated pulmonary component. The continuous machinery murmurs with similar features as seen in moderate and small sized ducts but with louder intensity (4/6 grade) could be heard.
  • An apical diastolic rumble due to increased flow across the mitral valve may be present
  • A third heart sound may be present.
  • If there is no reduction in the size of ductus, after age 2, progressive obstructive disease develops in these patients
    • Signs of heart failure develop
    • The JVP may be elevated due to RV failure. Prominent "a wave" due to diminished RV compliance and RVH.
    • Signs of pulmonary hypertension associated with right-to-left shunt start appearing.
    • As the pulmonary hypertension increases, left to right flow across the duct decreases and there is no audible murmur. A murmur of pulmonic insufficiency may be noted (Graham-Steell murmur) due to dilation of the pulmonic valve ring resulting from pulmonary hypertension. Flow into a dilated pulmonary trunk causes a pulmonic ejection sound and pulmonic ejection murmur. The second pulmonic heart sound is closely split or not split.

Extremities

  • Differential cyanosis i.e. cyanosis is more pronounced in lower extremities compared to upper.This is so because the ductus originates distal to the left subclavian artery. The left subclavian artery mainly supplies the upper extremities which escapes the shunting of blood.

References

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