Hepatitis D other diagnostic studies: Difference between revisions
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*Liver biopsy is not routinely indicated in diagnosis of acute hepatitis D unless the serologic diagnosis of hepatitis is inconclusive. However, liver biopsy is indicated in chronic liver disease to evaluate for [[cirrhosis]] or [[fibrosis]]. | *Liver biopsy is not routinely indicated in diagnosis of acute hepatitis D unless the serologic diagnosis of hepatitis is inconclusive. However, liver biopsy is indicated in chronic liver disease to evaluate for [[cirrhosis]] or [[fibrosis]]. | ||
*Histopathologic findings are similar to that observed in HBV infection. Acidophilic cytoplasm in hepatocytes with lymphocytic infiltrates may be observed. | *Histopathologic findings are similar to that observed in HBV infection. [[Acidophilic]] cytoplasm in hepatocytes with lymphocytic infiltrates may be observed. | ||
*Immunohistochemical staining may be positive for HDV antigen with suppression of HBsAg in case of superinfection. | *[[Immunohistochemical staining]] may be positive for HDV antigen with suppression of [[HBsAg]] in case of superinfection. | ||
==References== | ==References== |
Revision as of 20:00, 16 March 2012
Hepatitis D |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S. [2]
Liver Biopsy
- Liver biopsy is not routinely indicated in diagnosis of acute hepatitis D unless the serologic diagnosis of hepatitis is inconclusive. However, liver biopsy is indicated in chronic liver disease to evaluate for cirrhosis or fibrosis.
- Histopathologic findings are similar to that observed in HBV infection. Acidophilic cytoplasm in hepatocytes with lymphocytic infiltrates may be observed.
- Immunohistochemical staining may be positive for HDV antigen with suppression of HBsAg in case of superinfection.