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====Is there and an association between KAWASAKI disease and COVID-19?====
====Is there and an association between KAWASAKI disease and COVID-19?====
*Kawasaki disease, also known as lymph node syndrome, mucocutaneous node disease, infantile polyarteritis, and Kawasaki syndrome, is a poorly understood self-limited vasculitis that affects many organs, including the skin, mucous membranes, lymph nodes, blood vessel walls, and the heart.https://www.wikidoc.org/index.php/Kawasaki_disease_overview The emergence of COVID-19 has seen new presentations of known medical conditions for the first time.<ref name="urlAssociation Between COVID-19 and Kawasaki Disease: Vigilance Required From Otolaryngologists - Henya Sandhaus, Dana Crosby, Arun Sharma, Stacie R. Gregory,">{{cite web |url=https://journals.sagepub.com/doi/full/10.1177/0194599820930238 |title=Association Between COVID-19 and Kawasaki Disease: Vigilance Required From Otolaryngologists - Henya Sandhaus, Dana Crosby, Arun Sharma, Stacie R. Gregory, |format= |work= |accessdate=}}</ref> Numerous reports have shown a spike in new/concurrent cases of Kawasaki disease in COVID-19 positive patients. Information regarding the novel COVID-19 is still being gathered and although an exact association hasn't been established between Kawasaki disease and COVID-19, more research and investigations are still being conducted.<ref name="urlTrending Clinical Topic: Kawasaki Disease and COVID-19">{{cite web |url=https://reference.medscape.com/viewarticle/930287 |title=Trending Clinical Topic: Kawasaki Disease and COVID-19 |format= |work= |accessdate=}}</ref>
*Kawasaki disease, also known as lymph node syndrome, mucocutaneous node disease, infantile polyarteritis, and Kawasaki syndrome, is a poorly understood self-limited vasculitis that affects many organs, including the skin, mucous membranes, lymph nodes, blood vessel walls, and the heart.<ref name="urlKawasaki disease overview - wikidoc">{{cite web |url=https://www.wikidoc.org/index.php/Kawasaki_disease_overview |title=Kawasaki disease overview - wikidoc |format= |work= |accessdate=}}</ref> The emergence of COVID-19 has seen new presentations of known medical conditions for the first time.<ref name="urlAssociation Between COVID-19 and Kawasaki Disease: Vigilance Required From Otolaryngologists - Henya Sandhaus, Dana Crosby, Arun Sharma, Stacie R. Gregory,">{{cite web |url=https://journals.sagepub.com/doi/full/10.1177/0194599820930238 |title=Association Between COVID-19 and Kawasaki Disease: Vigilance Required From Otolaryngologists - Henya Sandhaus, Dana Crosby, Arun Sharma, Stacie R. Gregory, |format= |work= |accessdate=}}</ref> Numerous reports have shown a spike in new/concurrent cases of Kawasaki disease in COVID-19 positive patients. Information regarding the novel COVID-19 is still being gathered and although an exact association hasn't been established between Kawasaki disease and COVID-19, more research and investigations are still being conducted.<ref name="urlTrending Clinical Topic: Kawasaki Disease and COVID-19">{{cite web |url=https://reference.medscape.com/viewarticle/930287 |title=Trending Clinical Topic: Kawasaki Disease and COVID-19 |format= |work= |accessdate=}}</ref>


====Is Multi-system Inflammatory Syndrome in Children (MIS-C) fatal? What precautions can be taken to avoid it?====
====Is Multi-system Inflammatory Syndrome in Children (MIS-C) fatal? What precautions can be taken to avoid it?====

Revision as of 13:27, 20 June 2020

Frequently Asked Inpatient Questions Microchapter

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Pediatrics Related Questions

Are children with congenital heart diseases at increased risk of COVID-19?

  • A study published in the Journal of the American Heart Association investigated the effects of COVID-17 in the pediatric and adolescent population with congenital heart disease(CHD).[1] The results found that patients with CHD are more susceptible to being infected by COVID-19 and may in fact have worse outcomes and complications due to the disease. This is as a result of their already disturbed physiologic states as well as other co-morbidities associated with congenital heart diseases.[1] For these individuals, primary prevention and infection control processes are especially crucial.

Are children with underlying conditions at increased risk of hospitalization?

  • Almost all children infected with COVID-19 have excellent outcomes. However of those hospitalized due to the disease, the majority are children under the age of 1,[2][3] and those with underlying conditions. The most commonly reported conditions include:[2] [4]
    • pulmonary diseases i.e; asthma
    • congenital heart disease and other cardiovascular conditions
    • Immunosuppression due to cancer or any of its treatment therapies, high dose of glucocorticoids, e.t.c

Is there and an association between KAWASAKI disease and COVID-19?

  • Kawasaki disease, also known as lymph node syndrome, mucocutaneous node disease, infantile polyarteritis, and Kawasaki syndrome, is a poorly understood self-limited vasculitis that affects many organs, including the skin, mucous membranes, lymph nodes, blood vessel walls, and the heart.[5] The emergence of COVID-19 has seen new presentations of known medical conditions for the first time.[6] Numerous reports have shown a spike in new/concurrent cases of Kawasaki disease in COVID-19 positive patients. Information regarding the novel COVID-19 is still being gathered and although an exact association hasn't been established between Kawasaki disease and COVID-19, more research and investigations are still being conducted.[7]

Is Multi-system Inflammatory Syndrome in Children (MIS-C) fatal? What precautions can be taken to avoid it?

Should routinely-recommended Hepatitis A and B vaccines continue to be administered to children?

Should vaccinations for HBV exposed infants be continued during the COVID 19 pandemic?

Sources

  1. ↑ 1.0 1.1 Alsaied T, Aboulhosn JA, Cotts TB, Daniels CJ, Etheridge SP, Feltes TF, Gurvitz MZ, Lewin MB, Oster ME, Saidi A (June 2020). "Coronavirus Disease 2019 (COVID-19) Pandemic Implications in Pediatric and Adult Congenital Heart Disease". J Am Heart Assoc. 9 (12): e017224. doi:10.1161/JAHA.120.017224. PMID 32441586 Check |pmid= value (help).
  2. ↑ 2.0 2.1 "Coronavirus Disease 2019 in Children - United States, February 12-April 2, 2020". MMWR Morb. Mortal. Wkly. Rep. 69 (14): 422–426. April 2020. doi:10.15585/mmwr.mm6914e4. PMC 7147903 Check |pmc= value (help). PMID 32271728 Check |pmid= value (help).
  3. ↑ "Coronavirus Disease 2019 (COVID-19) Treatment Guidelines".
  4. ↑ "UpToDate".
  5. ↑ "Kawasaki disease overview - wikidoc".
  6. ↑ "Association Between COVID-19 and Kawasaki Disease: Vigilance Required From Otolaryngologists - Henya Sandhaus, Dana Crosby, Arun Sharma, Stacie R. Gregory,".
  7. ↑ "Trending Clinical Topic: Kawasaki Disease and COVID-19".
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