PURSUIT risk score: Difference between revisions
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|+PURSUIT Risk Score | |+PURSUIT Risk Score<ref name="pmid222949682">{{cite journal |vauthors=Backus BE, Six AJ, Kelder JH, Gibler WB, Moll FL, Doevendans PA |title=Risk scores for patients with chest pain: evaluation in the emergency department |journal=Curr Cardiol Rev |volume=7 |issue=1 |pages=2–8 |date=February 2011 |pmid=22294968 |pmc=3131711 |doi=10.2174/157340311795677662 |url=}}</ref> | ||
!Elements | !Elements | ||
!Entry | !Entry | ||
Revision as of 22:43, 11 February 2020
Definition and History
The PURSUIT (Platelet glycoprotein IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin Therapy) risk score was developed in a randomized clinical trial which recruited 9,461 patients and compared eptifibatide (Integrilin) to placebo in the management of Unstable Angina (UA) or Non-ST elevation Myocardial Infarction (NSTEMI).
Function
- By using multivariate regression analysis, the investigators established seven risk predictors for death and myocardial infarction (MI) in patients with acute coronary syndromes.
- Five of these risk factors were then combined into a scoring system:
- Higher age
- Sex
- Worst Canadian Cardiovascular Society (CCS) class of angina
- Signs of heart failure
- ST-segment depression on the index ECG
- Each of these elements is scored accordingly, resulting in a score ranging 1 - 18.
| Elements | Entry | Score |
|---|---|---|
| Age |
|
|
| Sex |
|
|
| Worst CCS class past 6 weeks |
|
|
| Signs of heart failure |
| |
| ST depression on ECG |
|
- ↑ Backus BE, Six AJ, Kelder JH, Gibler WB, Moll FL, Doevendans PA (February 2011). "Risk scores for patients with chest pain: evaluation in the emergency department". Curr Cardiol Rev. 7 (1): 2–8. doi:10.2174/157340311795677662. PMC 3131711. PMID 22294968.