Renal oncocytoma epidemiology and demographics: Difference between revisions

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{{Renal Oncocytoma}}
{{Renal Oncocytoma}}
{{CMG}}; {{AE}}{{Homa}} {{SC}}
{{CMG}}; {{AE}}{{Homa}} {{SC}}
===Age===
* The [[incidence]] of renal oncocytoma increases with age; the median age at diagnosis is 55 years.
Oncocytomas make up 3% to 7% of all renal epithelial tumors.[1] They are most commonly seen in adults older than 50 years, are more common in males, and have a peak frequency in the seventh decade of life. However, these tumors rarely occur in the pediatric population.[1]
This lesion is commonly seen in patients with Birt-Hogg-Dube syndrome. These patients develop a mean of 5.3 renal tumors in their lifetime. These lesions consist mostly of chromophobe renal carcinoma and oncocytomas


==Overview==
==Overview==
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*Males are more commonly affected by renal oncocytoma than females. The male to female ratio is approximately 2 to 1.<ref name="Yusenko2010">{{cite journal|last1=Yusenko|first1=Maria V|title=Molecular pathology of renal oncocytoma: A review|journal=International Journal of Urology|volume=17|issue=7|year=2010|pages=602–612|issn=09198172|doi=10.1111/j.1442-2042.2010.02574.x}}</ref>
*Males are more commonly affected by renal oncocytoma than females. The male to female ratio is approximately 2 to 1.<ref name="Yusenko2010">{{cite journal|last1=Yusenko|first1=Maria V|title=Molecular pathology of renal oncocytoma: A review|journal=International Journal of Urology|volume=17|issue=7|year=2010|pages=602–612|issn=09198172|doi=10.1111/j.1442-2042.2010.02574.x}}</ref>
   
   
The ages of patients with typical renal oncocytoma have varied considerably. Patients have ranged in age from 10 years to 94 years.3–6 The peak incidence of detection is in the seventh decade of life. This finding suggests that renal oncocytomas occur in a relatively older age group than in those patients with typical renal cell carcinoma (RCC), for whom the median age in large series is always approximately 55 years. However, taking into account that renal oncocytoma grows very slowly, it might start developing at an earlier age, around 30–50 years. For the cases of renal oncocytoma with reported sex, men are affected nearly twice as often as women
The peak incidence of detection is in the seventh decade of life. This finding suggests that renal oncocytomas occur in a relatively older age group than in those patients with typical renal cell carcinoma (RCC), for whom the median age in large series is always approximately 55 years. However, taking into account that renal oncocytoma grows very slowly, it might start developing at an earlier age, around 30–50 years. For the cases of renal oncocytoma with reported sex, men are affected nearly twice as often as women


The ratio of oncocytoma among male and female patients appears to be 2 to 3:1, similar to the ratio seen in renal cell carcinoma (RCC). Mean age at the time of resection in large series has ranged from 62 to 68 years of age [3•,4,7,8].
The ratio of oncocytoma among male and female patients appears to be 2 to 3:1, similar to the ratio seen in renal cell carcinoma (RCC). Mean age at the time of resection in large series has ranged from 62 to 68 years of age [3•,4,7,8].

Revision as of 18:27, 29 April 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Homa Najafi, M.D.[2] Shanshan Cen, M.D. [3]

Overview

Epidemiology and Demographics

Incidence

  • The incidence of renal oncocytoma is approximately 3% to 7% of solid renal resected tumors.[1][2]

Age

  • Patients of all age groups may develop renal oncocytoma. The age of patients can be differ from 10 to 94 years.[3][4][5]
  • The incidence of renal oncocytoma increases with age; the median age at the time of surgery is 62 to 68 years.

Gender

  • Males are more commonly affected by renal oncocytoma than females. The male to female ratio is approximately 2 to 1.[6]

The peak incidence of detection is in the seventh decade of life. This finding suggests that renal oncocytomas occur in a relatively older age group than in those patients with typical renal cell carcinoma (RCC), for whom the median age in large series is always approximately 55 years. However, taking into account that renal oncocytoma grows very slowly, it might start developing at an earlier age, around 30–50 years. For the cases of renal oncocytoma with reported sex, men are affected nearly twice as often as women

The ratio of oncocytoma among male and female patients appears to be 2 to 3:1, similar to the ratio seen in renal cell carcinoma (RCC). Mean age at the time of resection in large series has ranged from 62 to 68 years of age [3•,4,7,8].


References

  1. Rosenkrantz, Andrew B.; Hindman, Nicole; Fitzgerald, Erin F.; Niver, Benjamin E.; Melamed, Jonathan; Babb, James S. (2010). "MRI Features of Renal Oncocytoma and Chromophobe Renal Cell Carcinoma". American Journal of Roentgenology. 195 (6): W421–W427. doi:10.2214/AJR.10.4718. ISSN 0361-803X.
  2. B. Perez-Ordonez, G. Hamed, S. Campbell, R. A. Erlandson, P. Russo, P. B. Gaudin & V. E. Reuter (1997). "Renal oncocytoma: a clinicopathologic study of 70 cases". The American journal of surgical pathology. 21 (8): 871–883. PMID 9255250. Unknown parameter |month= ignored (help)
  3. H. Choi, U. A. Almagro, J. T. McManus, D. H. Norback & S. C. Jacobs (1983). "Renal oncocytoma. A clinicopathologic study". Cancer. 51 (10): 1887–1896. PMID 6831354. Unknown parameter |month= ignored (help)
  4. M. B. Amin, T. B. Crotty, S. K. Tickoo & G. M. Farrow (1997). "Renal oncocytoma: a reappraisal of morphologic features with clinicopathologic findings in 80 cases". The American journal of surgical pathology. 21 (1): 1–12. PMID 8990136. Unknown parameter |month= ignored (help)
  5. B. Perez-Ordonez, G. Hamed, S. Campbell, R. A. Erlandson, P. Russo, P. B. Gaudin & V. E. Reuter (1997). "Renal oncocytoma: a clinicopathologic study of 70 cases". The American journal of surgical pathology. 21 (8): 871–883. PMID 9255250. Unknown parameter |month= ignored (help)
  6. Yusenko, Maria V (2010). "Molecular pathology of renal oncocytoma: A review". International Journal of Urology. 17 (7): 602–612. doi:10.1111/j.1442-2042.2010.02574.x. ISSN 0919-8172.

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