Gonadoblastoma differential diagnosis: Difference between revisions

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Gonadoblastoma must be differentiated from other diseases that cause virilization, and primary amenorrhea and also must be differentiated pathologically from[[dysgerminoma]], Sex-cord stromal tumors, and Sertoli-cell nodules.
Gonadoblastoma must be differentiated from other diseases that cause virilization, and primary amenorrhea and also must be differentiated pathologically from[[dysgerminoma]], Sex-cord stromal tumors, and Sertoli-cell nodules.


==Differentiating [Disease name] from other Diseases==
==Differentiating Gonadoblastoma from other Diseases==
[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].
Gonadoblastoma must be differentiated from other diseases that cause disorders of sex development, ambiguous genitalia, virilization, and primary amenorrhea such as:
 
*17-Hydroxylase (17-OH) deficiency syndrome
OR
*Turner Syndrome
 
*Sweyer Syndrome
[Disease name] must be differentiated from [differential dx1], [differential dx2], and [differential dx3].
*5-Alpha-Reductase Deficiency
 
*Congenital adrenal hyperplasia
OR
*Hypospadias
 
*Undescended testis
As [disease name] manifests in a variety of clinical forms, differentiation must be established in accordance with the particular subtype. [Subtype name 1] must be differentiated from other diseases that cause [clinical feature 1], such as [differential dx1] and [differential dx2]. In contrast, [subtype name 2] must be differentiated from other diseases that cause [clinical feature 2], such as [differential dx3] and [differential dx4].
Gonadoblastoma must be differentiated pathologically from:<ref name="978-1-4557-4858-7">{{cite book | last = Sperling | first = M | title = Pediatric endocrinology | publisher = Elsevier/Saunders | location = Philadelphia, PA | year = 2014 | isbn = 978-1-4557-4858-7 }}</ref><ref>{{cite book | last = Eble | first = John | title = Pathology and genetics of tumours of the urinary system and male genital organs | publisher = IARC Press Oxford University Press (distributor | location = Lyon Oxford | year = 2004 | isbn = 9283224159 }}</ref>
 
*[[dysgerminoma]]
*Sex-cord stromal tumors
*Sertoli-cell nodules
===Differentiating [disease name] from other diseases on the basis of [symptom 1], [symptom 2], and [symptom 3]===
===Differentiating [disease name] from other diseases on the basis of [symptom 1], [symptom 2], and [symptom 3]===


Revision as of 18:44, 12 February 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Gonadoblastoma must be differentiated from other diseases that cause virilization, and primary amenorrhea and also must be differentiated pathologically fromdysgerminoma, Sex-cord stromal tumors, and Sertoli-cell nodules.

Differentiating Gonadoblastoma from other Diseases

Gonadoblastoma must be differentiated from other diseases that cause disorders of sex development, ambiguous genitalia, virilization, and primary amenorrhea such as:

  • 17-Hydroxylase (17-OH) deficiency syndrome
  • Turner Syndrome
  • Sweyer Syndrome
  • 5-Alpha-Reductase Deficiency
  • Congenital adrenal hyperplasia
  • Hypospadias
  • Undescended testis

Gonadoblastoma must be differentiated pathologically from:[1][2]

Differentiating [disease name] from other diseases on the basis of [symptom 1], [symptom 2], and [symptom 3]

On the basis [symptom 1], [symptom 2], and [symptom 3], [disease name] must be differentiated from [disease 1], [disease 2], [disease 3], [disease 4], [disease 5], and [disease 6].

Diseases Clinical manifestations Para-clinical findings Gold standard Additional findings
Symptoms Physical examination
Lab Findings Imaging Histopathology
Symptom 1 Symptom 2 Symptom 3 Physical exam 1 Physical exam 2 Physical exam 3 Lab 1 Lab 2 Lab 3 Imaging 1 Imaging 2 Imaging 3
Differential Diagnosis 1
Differential Diagnosis 2
Differential Diagnosis 3
Diseases Symptom 1 Symptom 2 Symptom 3 Physical exam 1 Physical exam 2 Physical exam 3 Lab 1 Lab 2 Lab 3 Imaging 1 Imaging 2 Imaging 3 Histopathology Gold standard Additional findings
Differential Diagnosis 4
Differential Diagnosis 5
Differential Diagnosis 6

References

  1. ↑ Sperling, M (2014). Pediatric endocrinology. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1-4557-4858-7.
  2. ↑ Eble, John (2004). Pathology and genetics of tumours of the urinary system and male genital organs. Lyon Oxford: IARC Press Oxford University Press (distributor. ISBN 9283224159.

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