Pleomorphic adenoma classification: Difference between revisions

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Revision as of 18:07, 28 January 2019

Pleomorphic adenoma Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Pleomorphic adenoma can be classified into 4 subgroups on the basis of histology appearance and stromal content into 4 groups. Subgroup 1, subgroup 2, subgroup 3, subgroup 4. It can also be classified based upon the component that predominates into 3 types, cellular, stroma rich, and mixed type.

Classification

  • Pleomorphic adenoma can be classified based on the stromal content of the tumor into the following subgroups.[1]
    • Subgroup 1 is the classical pleomorphic adenoma with a stroma content of 30-50%
    • subgroup 2 has a stroma content of 80%
    • subgroup 3 has a poor stroma content of 20-30% or less and an epithelial differentiation similar to subgroup 1
    • subgroup 4 has also a poor stroma content (6%) with a relatively monomorphic epithelial structure.
  • Depending upon which component predominates pleomorphic adenoma can also be classified into:[2]

References

  1. Seifert G, Langrock I, Donath K (December 1976). "[A pathological classification of pleomorphic adenoma of the salivary glands (author's transl)]". HNO (in German). 24 (12): 415–26. PMID 1002574.
  2. Zhan, Kevin Y.; Khaja, Sobia F.; Flack, Allen B.; Day, Terry A. (2016). "Benign Parotid Tumors". Otolaryngologic Clinics of North America. 49 (2): 327–342. doi:10.1016/j.otc.2015.10.005. ISSN 0030-6665.

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