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| {{Infobox_gene}} | | {{Infobox_gene}} |
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| This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication; this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene. [provided by RefSeq, Nov 2010]. | | This gene encodes a protein that is an important regulator of [[genome]] stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific [[endonuclease]], which can resolve [[DNA]] secondary structures that are formed during [[DNA repair|repair]] and [[genetic recombination|recombination]] processes. Two identical copies of this gene are located on the p arm of [[chromosome 16]] due to a segmental duplication; this record represents the more telomeric copy. [[Alternative splicing]] results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene. [provided by RefSeq, Nov 2010]. |
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| == References == | | == References == |
Revision as of 19:10, 20 February 2018
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) is a protein in humans that is encoded by the SLX1B gene.
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This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication; this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene. [provided by RefSeq, Nov 2010].
References
Further reading
