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==Overview==
==Overview==
Risk factors for development of [[Hemophilia A]] include being of male sex and having a positive [[family history]] of the disease.
Risk factors for development of [[Hemophilia A]] include being of male sex and having a positive [[family history]] of the disease.
It is of note that acquired forms of the disease occur in specific circumstances including Malignancies, Pregnancy, Autoimmune disorders, Certain medications; All of which could be considered as Hemophilia risk factor either. 


==Risk Factors==
==Risk Factors==
Common risk factors in the development of Hemophilia A are:
Common risk factors in the development of Hemophilia A are:
*Male sex
*Male sex
*Family history of [[bleeding]]<ref> How Hemophilia is Inherited | Hemophilia | NCBDDD | CDC. Available at http://www.cdc.gov/ncbddd/hemophilia/inheritance-pattern.html. Accessed on Sept 20, 2016 </ref>
*Family history of [[bleeding]]<ref>How Hemophilia is Inherited | Hemophilia | NCBDDD | CDC. Available at http://www.cdc.gov/ncbddd/hemophilia/inheritance-pattern.html. Accessed on Sept 20, 2016 </ref>
Best-studied risk factors of the acquired form of the disease include:
* Malignancies (mostly hematologic)
* Pregnancy
* Autoimmune disorders(Lupus erythematosus, Rheumatoid arthritis)
* Infections(Hepatitis C, AIDS)
* Certain Drugs consumption (e.g. Interferon-ą)
* Dermatological conditions(Pemphigus, Psoriasis)
Of note, the majority of reported acquired cases of Hemophilia are about Hemophilia A type. It appears that, the same as congenital form, acquired form of Hemophilia B is rarer than Hemophilia A too.
 
The remaining cases of acquired Hemophilia are idiopathic or the underlying etiology is not known yet.


==References==
==References==

Revision as of 14:04, 14 July 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Fahd Yunus, M.D. [2]

Overview

Risk factors for development of Hemophilia A include being of male sex and having a positive family history of the disease.

It is of note that acquired forms of the disease occur in specific circumstances including Malignancies, Pregnancy, Autoimmune disorders, Certain medications; All of which could be considered as Hemophilia risk factor either. 

Risk Factors

Common risk factors in the development of Hemophilia A are:

Best-studied risk factors of the acquired form of the disease include:

  • Malignancies (mostly hematologic)
  • Pregnancy
  • Autoimmune disorders(Lupus erythematosus, Rheumatoid arthritis)
  • Infections(Hepatitis C, AIDS)
  • Certain Drugs consumption (e.g. Interferon-ą)
  • Dermatological conditions(Pemphigus, Psoriasis)

Of note, the majority of reported acquired cases of Hemophilia are about Hemophilia A type. It appears that, the same as congenital form, acquired form of Hemophilia B is rarer than Hemophilia A too.

The remaining cases of acquired Hemophilia are idiopathic or the underlying etiology is not known yet.

References

  1. How Hemophilia is Inherited | Hemophilia | NCBDDD | CDC. Available at http://www.cdc.gov/ncbddd/hemophilia/inheritance-pattern.html. Accessed on Sept 20, 2016

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