Hemophilia A classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Fahd Yunus, M.D. [2]
Overview
Hemophilia A and B an C may be classified according to the amount of Factor VIII/ IX/ XI present respectively, resulting in either a mild, moderate, or severe form of the disease.[1]
Classification
Hemophilia A and B an C may be classified according to the amount of Factor VIII/ IX/ XI present respectively, resulting in either a mild, moderate, or severe form of the disease.
- Mild hemophilia – 5-40% of normal factor VIII/ IX activity in the blood
- Moderate hemophilia – 1-5% of normal factor VIII/ IX activity in the blood
- Severe hemophilia – less than 1% of normal factor VIII/ IX activity in the blood
Hemophilia C severity classification is different from A and B and severe Hemophilia C is defined when plasma factor XI concentration is less than 20 IU/dL[2].
References
- ↑ How is Hemophilia Diagnosed? – NHLBI, NIH. Available at http://www.nhlbi.nih.gov/health/health-topics/topics/hemophilia/diagnosis. Accessed on July 30, 2016
- ↑ Duga S, Salomon O (2013). "Congenital factor XI deficiency: an update". Semin Thromb Hemost. 39 (6): 621–31. doi:10.1055/s-0033-1353420. PMID 23929304.