Thrombocytopenia physical examination: Difference between revisions

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* lymphadenopathy
* lymphadenopathy


* hepatosplenomegaly,
* hepatosplenomegaly


* Signs of thrombosis (See 'When to worry about thrombosis' above.)
* Signs of thrombosis
{| class="wikitable"
{| class="wikitable"
!physical finding
!physical finding
!categories
!further explanations
!further explanations
!
|-
|-
|bleeding
|bleeding
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** overt mucusal bleeding
** overt mucusal bleeding
* other sites
* other sites
|
|<nowiki>- Bleeding into the skin in the form of </nowiki>[[Petechia|petechiae]], [[purpura]] or overt mucusal bleeding is common in thrombocytopenia. Thrombocytopenic Bleeding due to thrombocytopenia is different from the bleeding seen in [[Coagulopathy|coagulopathies]].
 
[[Wet purpura|- Wet purpura]] often suggests a higher probability of serious bleedings. [[Palpable purpura]] is not common in thrombocytopenia and is mostly seen in [[Vascular disease|vascular]] or [[Inflammatory disease|inflammatory diseases]].
 
- Bleeding may also happen in every other organ systems, including the [[gastrointestinal tract]] (eg. [[occult blood]] in the [[Human feces|stool]]) or [[genitourinary tract]] (eg. [[hematuria]]). In these settings, appropriate evaluation of bleeding is warranted even if the [[etiology]] of thrombocytopenia is clear.
|-
|-
|hepatosplenomegaly
|[[hepatosplenomegaly]]
|
|Hepatosplenomegaly may suggest one of these conditions:
|
* [[Hepato-biliary diseases|liver disease]]
* [[lymphoma]]
* other [[Hematologic disease|hematologic conditions]]
|[[Splenomegaly]] due to any etiology could result in mild thrombocytopenia.
|-
|-
|lymphadenopathy
|[[lymphadenopathy]]
|
|
* focal
* focal
* generalized
* generalized
|
|<nowiki>- Lymphadenopathy and coexisting thrombocytopenia could be a sign of:</nowiki>
* infection
* [[lymphoma]]
* other [[Cancer|malignancies]]
- Focal, tender lymphadenopathy most commonly suggests localized bacterial infection.
 
- Generalized lymphadenopathy could be a sign of acute [[Human Immunodeficiency Virus (HIV)|HIV]] infection.
|-
|-
|thromboses
|[[Thrombosis|thromboses]]
|
|<nowiki>-</nowiki>
|
|<nowiki>-</nowiki>
|}
|}



Revision as of 16:44, 28 June 2018

Thrombocytopenia Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor-In-Chief: Farbod Zahedi Tajrishi, M.D.

Overview

Physical Examination

A set of signs can be present in thrombocytopenia, each of which suggesting different potential underlying causes. These include:

  • signs of bleeding
  • lymphadenopathy
  • hepatosplenomegaly
  • Signs of thrombosis
physical finding categories further explanations
bleeding - Bleeding into the skin in the form of petechiae, purpura or overt mucusal bleeding is common in thrombocytopenia. Thrombocytopenic Bleeding due to thrombocytopenia is different from the bleeding seen in coagulopathies.

- Wet purpura often suggests a higher probability of serious bleedings. Palpable purpura is not common in thrombocytopenia and is mostly seen in vascular or inflammatory diseases.

- Bleeding may also happen in every other organ systems, including the gastrointestinal tract (eg. occult blood in the stool) or genitourinary tract (eg. hematuria). In these settings, appropriate evaluation of bleeding is warranted even if the etiology of thrombocytopenia is clear.

hepatosplenomegaly Hepatosplenomegaly may suggest one of these conditions: Splenomegaly due to any etiology could result in mild thrombocytopenia.
lymphadenopathy
  • focal
  • generalized
- Lymphadenopathy and coexisting thrombocytopenia could be a sign of:

- Focal, tender lymphadenopathy most commonly suggests localized bacterial infection.

- Generalized lymphadenopathy could be a sign of acute HIV infection.

thromboses - -

References

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