Hamman-Rich syndrome natural history, complications and prognosis: Difference between revisions
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===Complications=== | ===Complications=== | ||
*Common complications of [[Hamman-Rich syndrome|acute interstitial pneumonitis]] include:<ref name="pmid16172252">{{cite journal |vauthors=Matthay MA, Zimmerman GA |title=Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management |journal=Am. J. Respir. Cell Mol. Biol. |volume=33 |issue=4 |pages=319–27 |date=October 2005 |pmid=16172252 |pmc=2715340 |doi=10.1165/rcmb.F305 |url=}}</ref> | *Common complications of [[Hamman-Rich syndrome|acute interstitial pneumonitis]] include:<ref name="pmid16172252">{{cite journal |vauthors=Matthay MA, Zimmerman GA |title=Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management |journal=Am. J. Respir. Cell Mol. Biol. |volume=33 |issue=4 |pages=319–27 |date=October 2005 |pmid=16172252 |pmc=2715340 |doi=10.1165/rcmb.F305 |url=}}</ref> | ||
**Respiratory failure and its complications | **[[Respiratory failure]] and its complications | ||
***Pulmonary emboli | ***[[Pulmonary embolism|Pulmonary emboli]] | ||
***Barotrauma | ***[[Barotrauma]] | ||
***Pneumonia | ***[[Pneumonia]] | ||
***Gastrointestinal hemorrhage | ***[[Gastrointestinal bleeding|Gastrointestinal hemorrhage]] | ||
***Renal failure | ***[[Renal insufficiency|Renal failure]] | ||
**Progressive pulmonary fibrosis | **Progressive [[Interstitial lung disease|pulmonary fibrosis]] | ||
===Prognosis=== | ===Prognosis=== | ||
*Prognosis of [[Hamman-Rich syndrome|acute interstitial pneumonitis]] is poor.<ref name="pmid19095855">{{cite journal |vauthors=Avnon LS, Pikovsky O, Sion-Vardy N, Almog Y |title=Acute interstitial pneumonia-Hamman-Rich syndrome: clinical characteristics and diagnostic and therapeutic considerations |journal=Anesth. Analg. |volume=108 |issue=1 |pages=232–7 |date=January 2009 |pmid=19095855 |doi=10.1213/ane.0b013e318188af7a |url=}}</ref><ref name="pmid17475632">{{cite journal |vauthors=Parambil JG, Myers JL, Aubry MC, Ryu JH |title=Causes and prognosis of diffuse alveolar damage diagnosed on surgical lung biopsy |journal=Chest |volume=132 |issue=1 |pages=50–7 |date=July 2007 |pmid=17475632 |doi=10.1378/chest.07-0104 |url=}}</ref> | *Prognosis of [[Hamman-Rich syndrome|acute interstitial pneumonitis]] is poor.<ref name="pmid19095855">{{cite journal |vauthors=Avnon LS, Pikovsky O, Sion-Vardy N, Almog Y |title=Acute interstitial pneumonia-Hamman-Rich syndrome: clinical characteristics and diagnostic and therapeutic considerations |journal=Anesth. Analg. |volume=108 |issue=1 |pages=232–7 |date=January 2009 |pmid=19095855 |doi=10.1213/ane.0b013e318188af7a |url=}}</ref><ref name="pmid17475632">{{cite journal |vauthors=Parambil JG, Myers JL, Aubry MC, Ryu JH |title=Causes and prognosis of diffuse alveolar damage diagnosed on surgical lung biopsy |journal=Chest |volume=132 |issue=1 |pages=50–7 |date=July 2007 |pmid=17475632 |doi=10.1378/chest.07-0104 |url=}}</ref> | ||
*Most patients die because of acute respiratory failure or its complications. | *Most patients die because of acute [[respiratory failure]] or its complications. | ||
*Mortality rate is very high, more than half of the patients die within 2 months. Patients who survive the initial hospitalization die within six months of presentation of disease. | *[[Mortality rate]] is very high, more than half of the patients die within 2 months. [[Patient|Patients]] who survive the initial [[hospitalization]] die within six months of presentation of disease. | ||
*Recurrence of the disease and progression to chronic interstitial lung disease can occur among survivors. | *Recurrence of the disease and progression to chronic [[interstitial lung disease]] can occur among survivors. | ||
==References== | ==References== |
Revision as of 00:02, 25 March 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.
- The symptoms of (disease name) typically develop ___ years after exposure to ___.
- If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
Complications
- Common complications of acute interstitial pneumonitis include:[1]
- Respiratory failure and its complications
- Progressive pulmonary fibrosis
Prognosis
- Prognosis of acute interstitial pneumonitis is poor.[2][3]
- Most patients die because of acute respiratory failure or its complications.
- Mortality rate is very high, more than half of the patients die within 2 months. Patients who survive the initial hospitalization die within six months of presentation of disease.
- Recurrence of the disease and progression to chronic interstitial lung disease can occur among survivors.
References
- ↑ Matthay MA, Zimmerman GA (October 2005). "Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management". Am. J. Respir. Cell Mol. Biol. 33 (4): 319–27. doi:10.1165/rcmb.F305. PMC 2715340. PMID 16172252.
- ↑ Avnon LS, Pikovsky O, Sion-Vardy N, Almog Y (January 2009). "Acute interstitial pneumonia-Hamman-Rich syndrome: clinical characteristics and diagnostic and therapeutic considerations". Anesth. Analg. 108 (1): 232–7. doi:10.1213/ane.0b013e318188af7a. PMID 19095855.
- ↑ Parambil JG, Myers JL, Aubry MC, Ryu JH (July 2007). "Causes and prognosis of diffuse alveolar damage diagnosed on surgical lung biopsy". Chest. 132 (1): 50–7. doi:10.1378/chest.07-0104. PMID 17475632.