Hepatocellular carcinoma classification: Difference between revisions

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==Overview==
==Overview==


[Disease name] may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].
Hepatocellular carcinoma may be classified according to the histological subtypes. The staging of HCC is based on the TNM staging system.


OR
==Classification ==


[Disease name] may be classified into [large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3].
*Hepatocellular carcinoma may be classified according to the histological subtypes:<ref name="pmid26838979">{{cite journal |vauthors=Shafizadeh N, Kakar S |title=Hepatocellular Carcinoma: Histologic Subtypes |journal=Surg Pathol Clin |volume=6 |issue=2 |pages=367–84 |year=2013 |pmid=26838979 |doi=10.1016/j.path.2013.03.007 |url=}}</ref>
[Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].
 
OR
 
Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
 
OR
 
If the staging system involves specific and characteristic findings and features:
According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
 
OR
 
The staging of [malignancy name] is based on the [staging system].
 
OR
 
There is no established system for the staging of [malignancy name].
 
==Classification==
 
*Hepatocellular carcinoma may be classified according to the histological subtypes:
**Fibrolamellar carcinoma sarcomatoid HCC  
**Fibrolamellar carcinoma sarcomatoid HCC  
**Undifferentiated carcinoma
**Undifferentiated carcinoma
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==Staging==
==Staging==


According to the TNM staging system, there are four stages of hepatocellular carcinoma based on the tumor size, lymph node involvement, and distant metastasis.<ref name="cancerca"> Canadian Cancer Society.http://www.cancer.ca/en/cancer-information/cancer-type/liver/staging/?region=ab</ref>
According to the TNM staging system, there are four stages of hepatocellular carcinoma based on the tumor size, lymph node involvement, and distant metastasis.<ref name="cancerca">Canadian Cancer Society.http://www.cancer.ca/en/cancer-information/cancer-type/liver/staging/?region=ab</ref>


===Primary tumor===
===Primary tumor===
{| {{table}}
{| {{table}} cellpadding="4" cellspacing="0" style="border:#c9c9c9 1px solid; margin: 1em 1em 1em 0; border-collapse: collapse;"
||TX
||TX
||Primary tumour cannot be assessed
||Primary tumour cannot be assessed
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===Regional lymph node===
===Regional lymph node===


{| {{table}}
{| {{table}} cellpadding="4" cellspacing="0" style="border:#c9c9c9 1px solid; margin: 1em 1em 1em 0; border-collapse: collapse;"
| NX||Regional lymph nodes cannot be assessed
| NX||Regional lymph nodes cannot be assessed
|-
|-
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===Distance metastasis===
===Distance metastasis===


{| {{table}}
{| {{table}} cellpadding="4" cellspacing="0" style="border:#c9c9c9 1px solid; margin: 1em 1em 1em 0; border-collapse: collapse;"
| M0||No distant metastasis
| M0||No distant metastasis
|-
|-

Revision as of 04:54, 27 December 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: {SH}

Overview

Hepatocellular carcinoma may be classified according to the histological subtypes. The staging of HCC is based on the TNM staging system.

Classification

  • Hepatocellular carcinoma may be classified according to the histological subtypes:[1]
    • Fibrolamellar carcinoma sarcomatoid HCC
    • Undifferentiated carcinoma
    • Combined HCC-cholangiocarcinoma (HCC-CC)
    • Lymphoepithelioma

Staging

According to the TNM staging system, there are four stages of hepatocellular carcinoma based on the tumor size, lymph node involvement, and distant metastasis.[2]

Primary tumor

TX Primary tumour cannot be assessed
T0 No evidence of primary tumour
T1 A single tumour with no invasion into the blood vessels of the liver
T2 A single tumour with invasion into the blood vessels or multiple tumours, none more than 5 cm in size
T3a Multiple tumours, with any tumour larger than 5 cm
T3b The tumour has grown into either the portal or hepatic vein
T4 The tumour has grown into nearby organs (other than the gallbladder) or the tumour has grown into the layer of tissue that covers the organs in the abdomen (visceral peritoneum)

Regional lymph node

NX Regional lymph nodes cannot be assessed
NX No regional lymph node metastasis
NX Regional lymph node metastasis

Distance metastasis

M0 No distant metastasis
M1 Distant metastasis

References

  1. ↑ Shafizadeh N, Kakar S (2013). "Hepatocellular Carcinoma: Histologic Subtypes". Surg Pathol Clin. 6 (2): 367–84. doi:10.1016/j.path.2013.03.007. PMID 26838979.
  2. ↑ Canadian Cancer Society.http://www.cancer.ca/en/cancer-information/cancer-type/liver/staging/?region=ab

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