Retinoblastoma differential diagnosis: Difference between revisions
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==Overview== | ==Overview== | ||
Retinoblastoma must be differentiated from other diseases that cause leukocoria, such as congenital cataract, persistent fetal vasculature, Coats disease, cloboma of choroid or optic disc, toxocariasis, astrocytic hamartoma, retinopathy of prematurity, vitreous hemorrhage, uveitis, retinal dysplasia, and medulloepithelioma. | Retinoblastoma must be differentiated from other diseases that cause leukocoria, such as congenital cataract, persistent fetal vasculature, Coats disease, cloboma of choroid or optic disc, toxocariasis, astrocytic hamartoma, retinopathy of prematurity, vitreous hemorrhage, uveitis, retinal dysplasia, and medulloepithelioma.<ref name="wiki"> Retinoblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Retinoblastoma#cite_note-30 Accessed on October 2 2015</ref> | ||
==Differential diagnosis== | ==Differential diagnosis== | ||
The common causes of leukocoria in children include:<ref name="wiki"> Retinoblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Retinoblastoma#cite_note-30 Accessed on October 2 2015</ref> | Retinoblastoma must be differentiated from other diseases that cause leukocoria. The common causes of leukocoria in children include:<ref name="wiki"> Retinoblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Retinoblastoma#cite_note-30 Accessed on October 2 2015</ref> | ||
*Congenital cataract | *Congenital cataract | ||
*Persistent fetal vasculature | *Persistent fetal vasculature | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Ophthalmology]] | [[Category:Ophthalmology]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:hereditary cancers]] | [[Category:hereditary cancers]] |
Revision as of 14:33, 15 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1],Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Retinoblastoma must be differentiated from other diseases that cause leukocoria, such as congenital cataract, persistent fetal vasculature, Coats disease, cloboma of choroid or optic disc, toxocariasis, astrocytic hamartoma, retinopathy of prematurity, vitreous hemorrhage, uveitis, retinal dysplasia, and medulloepithelioma.[1]
Differential diagnosis
Retinoblastoma must be differentiated from other diseases that cause leukocoria. The common causes of leukocoria in children include:[1]
- Congenital cataract
- Persistent fetal vasculature
- Coats disease
Less common causes of leukocoria include:
- Coloboma of choroid or optic disc
- Toxocariasis
- Astrocytic hamartoma
- Retinopathy of prematurity (stage 4, 5)
- Vitreous hemorrhage
- Uveitis (pars planitis)
- Retinal dysplasia
- Medulloepithelioma
Differentiating features of some common and less common differential diagnosis are:
Disease/Condition | Differentiating Signs/Symptoms | Differentiating Tests |
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Congenital Cataract |
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Coats disease (exudative retinitis or retinal telangiectasis) |
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Persistent fetal vasculature (formerly known as persistent hyperplastic primary vitreous) |
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Retinopathy of prematurity (ROP) |
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Ocular toxocariasis |
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References
- ↑ 1.0 1.1 Retinoblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Retinoblastoma#cite_note-30 Accessed on October 2 2015