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==[[B-cell prolymphocytic leukemia pathophysiology|Pathophysiology]]==
==[[B-cell prolymphocytic leukemia pathophysiology|Pathophysiology]]==
B-cell prolymphocytic leukemia arises from mature B-cells, which are hematologic white cells that are normally involved in the in the [[humoral immunity]] component of the adaptive immune system by secreting [[antibodies]].


==[[B-cell prolymphocytic leukemia differential diagnosis|Differentiating B-cell prolymphocytic leukemia from other Diseases]]==
==[[B-cell prolymphocytic leukemia differential diagnosis|Differentiating B-cell prolymphocytic leukemia from other Diseases]]==
B-cell prolymphocytic leukemia must be differentiated from other diseases such as [[T-cell prolymphocytic leukemia]], [[chronic lymphocytic leukemia]] and [[hairy cell leukemia]].


==[[B-cell prolymphocytic leukemia epidemiology and demographics|Epidemiology and Demographics]]==
==[[B-cell prolymphocytic leukemia epidemiology and demographics|Epidemiology and Demographics]]==
The incidence of B-cell prolymphocytic leukemia is 1% of lymphocytic leukemias. B-cell prolymphocytic leukemia affects men and women equally.


==[[B-cell prolymphocytic leukemia risk factors|Risk Factors]]==
==[[B-cell prolymphocytic leukemia risk factors|Risk Factors]]==
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==[[B-cell prolymphocytic leukemia natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
==[[B-cell prolymphocytic leukemia natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
The prognosis for B-cell prolymphocytic leukemia is generally poor.


==Diagnosis==
==Diagnosis==

Revision as of 14:29, 7 October 2015

B-cell prolymphocytic leukemia

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Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating B-cell prolymphocytic leukemia from other Diseases

Epidemiology and Demographics

Risk Factors

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Natural History, Complications and Prognosis

Diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Carlos A Lopez, M.D. [2]

Synonyms and keywords: B-PLL, Prolymphocytic leukemia, B-cell type

Overview

B-cell prolymphocytic leukemia is a form of leukemia or cancer of the white blood cells

Historical Perspective

Classification

Pathophysiology

B-cell prolymphocytic leukemia arises from mature B-cells, which are hematologic white cells that are normally involved in the in the humoral immunity component of the adaptive immune system by secreting antibodies.

Differentiating B-cell prolymphocytic leukemia from other Diseases

B-cell prolymphocytic leukemia must be differentiated from other diseases such as T-cell prolymphocytic leukemia, chronic lymphocytic leukemia and hairy cell leukemia.

Epidemiology and Demographics

The incidence of B-cell prolymphocytic leukemia is 1% of lymphocytic leukemias. B-cell prolymphocytic leukemia affects men and women equally.

Risk Factors

Screening

Natural History, Complications and Prognosis

The prognosis for B-cell prolymphocytic leukemia is generally poor.

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | CT | MRI | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

References