Multiple endocrine neoplasia type 2 (patient information): Difference between revisions
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{{CMG}}; {{AE}} {{Ammu}} | {{CMG}}; {{AE}} {{Ammu}} | ||
==Overview== | ==Overview== | ||
* Multiple endocrine neoplasia (MEN) type II is a [[disease]] passed down through families, in which one or more of the [[endocrine gland]]s are overactive or form a [[tumor]]. [[Endocrine gland]]s most commonly involved include [[adrenal]], [[parathyroid]] and [[thyroid]]. | * Multiple endocrine neoplasia (MEN) type II is a [[disease]] passed down through families, in which one or more of the [[endocrine gland]]s are overactive or form a [[tumor]]. [[Endocrine gland]]s most commonly involved include [[adrenal]] gland, [[parathyroid]] gland and [[thyroid]] gland. | ||
==What are the symptoms of multiple endocrine neoplasia type 2?== | ==What are the symptoms of multiple endocrine neoplasia type 2?== | ||
* Cough | |||
* Diarrhea | |||
* Lump on the neck | |||
* Breathing difficulty | |||
* Chest pain | |||
* Abdominal pain | |||
* Nervousness | |||
* Pallor | |||
* Irritability | |||
* Headache | |||
* Sweating | |||
* Weight loss | |||
* Palpitations | |||
* Tremor | |||
* Insomnia | |||
* Constipation | |||
* Lethargy | |||
* Muscle pain | |||
* Nausea | |||
* Increased frequency of urination | |||
* Confusion | |||
* Nausea | |||
* Bone fractures | |||
==What causes multiple endocrine neoplasia type 2?== | ==What causes multiple endocrine neoplasia type 2?== | ||
* MEN2 is an inherited disorder that causes [[tumor]]s in the [[endocrine gland]]s | * MEN2 is an inherited disorder that causes [[tumor]]s in the [[endocrine gland]]s. Genetic [[mutation]]s is speculated to be the cause of the [[disease]]. | ||
==Who is at highest risk?== | ==Who is at highest risk?== | ||
* Positive [[family history]] | * Positive [[family history]] | ||
* Multifocal or recurrent [[neoplasia]] | * Multifocal or recurrent [[neoplasia]] | ||
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==Treatment options== | ==Treatment options== | ||
* MEN2 cannot be cured, but regular testing can detect the problems caused by MEN2 [[tumor]]s many years before serious complications develop. | * MEN2 cannot be cured, but regular testing can detect the problems caused by MEN2 [[tumor]]s many years before serious complications develop. | ||
* Surgery is indicated for | * Surgery is indicated for thyroid tumors, adrenal tumors and parathyroid tumors. | ||
==Where to find medical care for multiple endocrine neoplasia type | ==Where to find medical care for multiple endocrine neoplasia type 2?== | ||
[http://maps.google.com/maps?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|map+top+hospital+Multiple endocrine neoplasia type 1}}}}&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&ie=UTF-8&sa=N&hl=en&tab=wl Directions to Hospitals Treating Multiple endocrine neoplasia type 1] | [http://maps.google.com/maps?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|map+top+hospital+Multiple endocrine neoplasia type 1}}}}&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&ie=UTF-8&sa=N&hl=en&tab=wl Directions to Hospitals Treating Multiple endocrine neoplasia type 1] | ||
==Prevention== | ==Prevention== | ||
* [[Screening]] people with [[family history]] of MEN | * [[Screening]] people with [[family history]] of MEN 2 is recommended. | ||
==What to expect (Outlook/Prognosis)?== | ==What to expect (Outlook/Prognosis)?== | ||
* | * Prognosis of the disease depends on the stage at which it is diagnosed. Early diagnosis and treatment is associated with better prognosis. | ||
==Possible complications== | ==Possible complications== | ||
* | * Metastasis | ||
* | * Osteoporosis | ||
* | * Kidney stones | ||
* | * Fractures | ||
* Hypoparathyroidism from parathyroidectomy | |||
==Sources== | ==Sources== | ||
* https://www.nlm.nih.gov/medlineplus/ency/article/000399.htm | |||
* https://www.nlm.nih.gov/medlineplus/ency/article/ | |||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Patient information]] | [[Category:Patient information]] | ||
[[Category:Oncology patient information]] | [[Category:Oncology patient information]] | ||
Revision as of 16:17, 27 September 2015
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Multiple endocrine neoplasia type 2 |
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Where to find medical care for Multiple endocrine neoplasia type 2? |
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Multiple endocrine neoplasia type 2 On the Web |
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Directions to Hospitals Treating Multiple endocrine neoplasia type 2 |
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Risk calculators and risk factors for Multiple endocrine neoplasia type 2 |
Template:WikiDoc Sources
For the WikiDoc page for this topic, click here.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
- Multiple endocrine neoplasia (MEN) type II is a disease passed down through families, in which one or more of the endocrine glands are overactive or form a tumor. Endocrine glands most commonly involved include adrenal gland, parathyroid gland and thyroid gland.
What are the symptoms of multiple endocrine neoplasia type 2?
- Cough
- Diarrhea
- Lump on the neck
- Breathing difficulty
- Chest pain
- Abdominal pain
- Nervousness
- Pallor
- Irritability
- Headache
- Sweating
- Weight loss
- Palpitations
- Tremor
- Insomnia
- Constipation
- Lethargy
- Muscle pain
- Nausea
- Increased frequency of urination
- Confusion
- Nausea
- Bone fractures
What causes multiple endocrine neoplasia type 2?
- MEN2 is an inherited disorder that causes tumors in the endocrine glands. Genetic mutations is speculated to be the cause of the disease.
Who is at highest risk?
- Positive family history
- Multifocal or recurrent neoplasia
- Two or more organ systems tumor involvement
Diagnosis
- MEN2 is detected by gene testing or, when gene testing is unavailable or yields a negative result, by laboratory tests that measure hormone levels. Less often, MEN2 is diagnosed based on an individual's medical and family history.
When to seek urgent medical care?
- Seek urgent medical care if there are symptoms of MEN 2 or its complications.
Treatment options
- MEN2 cannot be cured, but regular testing can detect the problems caused by MEN2 tumors many years before serious complications develop.
- Surgery is indicated for thyroid tumors, adrenal tumors and parathyroid tumors.
Where to find medical care for multiple endocrine neoplasia type 2?
Directions to Hospitals Treating Multiple endocrine neoplasia type 1
Prevention
- Screening people with family history of MEN 2 is recommended.
What to expect (Outlook/Prognosis)?
- Prognosis of the disease depends on the stage at which it is diagnosed. Early diagnosis and treatment is associated with better prognosis.
Possible complications
- Metastasis
- Osteoporosis
- Kidney stones
- Fractures
- Hypoparathyroidism from parathyroidectomy