Retinoblastoma natural history, complications, and prognosis: Difference between revisions
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Revision as of 17:28, 4 September 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Retinoblastoma Microchapters |
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Overview
If left untreated, the tumor fills the eye and completely destroys the globe in six months .Retinoblastoma is a rapidly growing tumor. Metastatic spread begins after six months and metastasized tumor is very rare at presentation. The tumor may spread through the subarachnoid space to the contralateral optic nerve or through the cerebrospinal fluid to the central nervous system or hematogenously to the lung, bone, or brain or by lymphatics if the tumor spreads anteriorly into the conjunctivae and eyelids, or extends into extraocular tissue. The most common routes of metastatic spread are direct infiltration via the optic nerve to the central nervous system, or spread via the choroid to the orbit. If untreated, death usually occurs in few years.
Natural History
Complications
Prognosis
The prognosis of retinoblastoma depends on the following:
- Whether or not the tumor can be removed by surgery.
- The stage of the cancer: the size of the tumor, whether the cancer has spread
- The child’s general health
Survival
Possible complications
- Local spread of tumor.
- Development of other tumors.
- Cataract from radiotherapy.
- Failure of tooth eruption after radiotherapy.
- Bony deformities
References
See also
Template:Nervous tissue tumors