Peutz-Jeghers syndrome secondary prevention: Difference between revisions
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{{CMG}} {{AE}} {{HQ}} | {{CMG}} {{AE}} {{HQ}} | ||
==Overview== | ==Overview== | ||
Secondary prevention strategies to detect intestinal and extraintestinal malignancies in Peutz-Jeghers syndrome include [[enteroscopy]] and [[colonoscopy]]. | Secondary prevention strategies to detect intestinal and extraintestinal malignancies in Peutz-Jeghers syndrome include [[enteroscopy]] and [[colonoscopy]]. | ||
==Secondary Prevention== | ==Secondary Prevention== | ||
At time of diagnosis, screening for cancerous lesions among patients with Peutz-Jeghers syndrome include the following:<ref name="SyngalBrand2015">{{cite journal|last1=Syngal|first1=Sapna|last2=Brand|first2=Randall E|last3=Church|first3=James M|last4=Giardiello|first4=Francis M|last5=Hampel|first5=Heather L|last6=Burt|first6=Randall W|title=ACG Clinical Guideline: Genetic Testing and Management of Hereditary Gastrointestinal Cancer Syndromes|journal=The American Journal of Gastroenterology|volume=110|issue=2|year=2015|pages=223–262|issn=0002-9270|doi=10.1038/ajg.2014.435}}</ref> | At time of diagnosis, screening for cancerous lesions among patients with Peutz-Jeghers syndrome include the following:<ref name="SyngalBrand2015">{{cite journal|last1=Syngal|first1=Sapna|last2=Brand|first2=Randall E|last3=Church|first3=James M|last4=Giardiello|first4=Francis M|last5=Hampel|first5=Heather L|last6=Burt|first6=Randall W|title=ACG Clinical Guideline: Genetic Testing and Management of Hereditary Gastrointestinal Cancer Syndromes|journal=The American Journal of Gastroenterology|volume=110|issue=2|year=2015|pages=223–262|issn=0002-9270|doi=10.1038/ajg.2014.435}}</ref><ref> Peutz-Jeghers syndrome https://online.epocrates.com/u/29441128/Peutz-Jeghers+syndrome</ref> | ||
*Small bowel video capsule endoscopy (every 3 years) | *Small bowel video capsule endoscopy (every 3 years) | ||
*Stomach [[Esophagogastroduodenoscopy]] (every 3 years) | *Stomach [[Esophagogastroduodenoscopy]] (every 3 years) | ||
Revision as of 17:05, 17 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]
Overview
Secondary prevention strategies to detect intestinal and extraintestinal malignancies in Peutz-Jeghers syndrome include enteroscopy and colonoscopy.
Secondary Prevention
At time of diagnosis, screening for cancerous lesions among patients with Peutz-Jeghers syndrome include the following:[1][2]
- Small bowel video capsule endoscopy (every 3 years)
- Stomach Esophagogastroduodenoscopy (every 3 years)
- Colonoscopy (every 3 years)
- Pancreas (every 1-2 years)
- Abdominal CT
- Pelvic ultrasound (annually)
- Testicular exam (annually)
- If abnormalities palpable perform an ultrasound
- Mammography starting at age 25 (annually)
- Endometrial pelvic exam and ultrasound (annually)
- Cervical Papanicolaou test (Pap test) (annually).
- Physical examination that includes evaluation of the breasts, abdomen, pelvis, and testes should be performed by a physician (annually)
- Complete blood count (CBC) to check for anemia should be done (annually)
References
- ↑ Syngal, Sapna; Brand, Randall E; Church, James M; Giardiello, Francis M; Hampel, Heather L; Burt, Randall W (2015). "ACG Clinical Guideline: Genetic Testing and Management of Hereditary Gastrointestinal Cancer Syndromes". The American Journal of Gastroenterology. 110 (2): 223–262. doi:10.1038/ajg.2014.435. ISSN 0002-9270.
- ↑ Peutz-Jeghers syndrome https://online.epocrates.com/u/29441128/Peutz-Jeghers+syndrome