Acrodermatitis chronica atrophicans pathophysiology: Difference between revisions

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{{CMG}}; {{AE}} {{RT}}
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==Overview==
 
==Pathophysiology==
==Pathophysiology==
This progressive skin process is due to the effect of continuing active infection with the [[spirochete]] [[Lyme disease microbiology|Borrelia afzelii]]. B afzelii is the predominant pathophysiology, but may not be the exclusive, [[etiology|etiologic]] agent of ACA. Borrelia garinii, has also been detected.
===Pathogenesis===
 
*This progressive [[skin]] process is due to the effect of [[Chronic (medical)|chronic]] [[infection]] with the [[spirochete]] [[borrelia burgdorferi]]. [[Borrelia|Borrelia afzelii]] is the predominant [[pathophysiology]], but may not be the exclusive, [[etiology]] of [[acrodermatitis chronica atrophicans]].  
*[[Borrelia|Borrelia garinii]] has also been detected in some [[patients]].
==Genetics==
==Associated Conditions==
Conditions associated with [disease name] include:
==Gross Pathology==
On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
===Microscopic Pathology===
===Microscopic Pathology===
* Light and electron microscopic study of the [[skin biopsy]] shows degeneration of the [[elastica]] and [[collagen]] fibers.<ref name="pmid7751475">{{cite journal |author=de Koning J, Tazelaar DJ, Hoogkamp-Korstanje JA, Elema JD |title=Acrodermatitis chronica atrophicans: a light and electron microscopic study |journal=J. Cutan. Pathol. |volume=22 |issue=1 |pages=23–32 |year=1995 |month=February |pmid=7751475 |doi= |url=}}</ref>
*[[Microscopy|Light]] and [[Electron microscope|electron microscopic study]] of the [[skin]] [[biopsy]] shows degeneration of the [[Descemet's membrane|elastica]] and [[collagen]] fibers.<ref name="pmid7751475">{{cite journal |author=de Koning J, Tazelaar DJ, Hoogkamp-Korstanje JA, Elema JD |title=Acrodermatitis chronica atrophicans: a light and electron microscopic study |journal=J. Cutan. Pathol. |volume=22 |issue=1 |pages=23–32 |year=1995 |month=February |pmid=7751475 |doi= |url=}}</ref>


==References==
==References==
{{reflist|2}}
{{reflist|2}}


[[Category:Needs content]]
[[Category:Needs review]]
[[Category:Disease]]
[[Category:Disease]]
[[Category:Dermatology]]
[[Category:Dermatology]]

Revision as of 13:05, 2 June 2021

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anahita Deylamsalehi, M.D.[2] Raviteja Guddeti, M.B.B.S. [3]

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Overview

Pathophysiology

Pathogenesis

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Conditions associated with [disease name] include:

Gross Pathology

On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].

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References

  1. de Koning J, Tazelaar DJ, Hoogkamp-Korstanje JA, Elema JD (1995). "Acrodermatitis chronica atrophicans: a light and electron microscopic study". J. Cutan. Pathol. 22 (1): 23–32. PMID 7751475. Unknown parameter |month= ignored (help)

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