Descemet's membrane is the basement membrane that lies between the corneal proper substance, also called stroma, and the endothelial layer of the cornea. The endothelial layer is located at the posterior of the cornea. Descemet's membrane, as the basement membrane for the endothelial layer, is secreted by the single layer of cuboidal epithelial cells that compose the endothelial layer of the cornea.
Its thickness ranges from 3 μm at birth to 8-10 μm in adults. 
It is also known as the Posterior limiting lamina, posterior elastic lamina, lamina elastica posterior, and membrane of Demours. It was named after French physician Jean Descemet (1732-1810).
- Johnson DH, Bourne WM, Campbell RJ: The ultrastructure of Descemet's membrane. I. Changes with age in normal cornea. Arch Ophthalmol 100:1942, 1982
- Histology image: 08002loa – Histology Learning System at Boston University
- Descemet+membrane at the US National Library of Medicine Medical Subject Headings (MeSH)
- Diagram at dryeyezone.com