Hepatic encephalopathy laboratory findings: Difference between revisions
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*[[Potassium]] level in the blood | *[[Potassium]] level in the blood | ||
*[[BUN]] and [[creatinine]] to see how the kidneys are working | *[[BUN]] and [[creatinine]] to see how the kidneys are working | ||
An ammonia level more than 200 strongly suggests hepatic encephalopathy.<ref name="pmid12637132">{{cite journal| author=Ong JP, Aggarwal A, Krieger D, Easley KA, Karafa MT, Van Lente F et al.| title=Correlation between ammonia levels and the severity of hepatic encephalopathy. | journal=Am J Med | year= 2003 | volume= 114 | issue= 3 | pages= 188-93 | pmid=12637132 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12637132 }} </ref> | |||
Ammonia levels over 123 are likely to improve with lactulose therapy.<ref name="pmid19555401">{{cite journal| author=Sharma P, Sharma BC, Sarin SK| title=Predictors of nonresponse to lactulose for minimal hepatic encephalopathy in patients with cirrhosis. | journal=Liver Int | year= 2009 | volume= 29 | issue= 9 | pages= 1365-71 | pmid=19555401 | doi=10.1111/j.1478-3231.2009.02067.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19555401 }} </ref> | |||
The inhibitory control test (ICT) may be a faster way to diagnose hepatic encephalopathy than standard psychometric tests (average administration time of 15 minutes versus 37 minutes).<ref name="pmid17222319">{{cite journal |author=Bajaj JS, Saeian K, Verber MD, ''et al'' |title=Inhibitory control test is a simple method to diagnose minimal hepatic encephalopathy and predict development of overt hepatic encephalopathy |journal=Am. J. Gastroenterol. |volume=102 |issue=4 |pages=754-60 |year=2007 |pmid=17222319 |doi=10.1111/j.1572-0241.2007.01048.x}}</ref> | The inhibitory control test (ICT) may be a faster way to diagnose hepatic encephalopathy than standard psychometric tests (average administration time of 15 minutes versus 37 minutes).<ref name="pmid17222319">{{cite journal |author=Bajaj JS, Saeian K, Verber MD, ''et al'' |title=Inhibitory control test is a simple method to diagnose minimal hepatic encephalopathy and predict development of overt hepatic encephalopathy |journal=Am. J. Gastroenterol. |volume=102 |issue=4 |pages=754-60 |year=2007 |pmid=17222319 |doi=10.1111/j.1572-0241.2007.01048.x}}</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
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Overview
Laboratory Findings
Tests may include:
- Complete blood count or hematocrit to check for anemia
- Liver function tests
- Prothrombin time
- Serum ammonia levels
- Sodium level in the blood
- Potassium level in the blood
- BUN and creatinine to see how the kidneys are working
An ammonia level more than 200 strongly suggests hepatic encephalopathy.[1]
Ammonia levels over 123 are likely to improve with lactulose therapy.[2]
The inhibitory control test (ICT) may be a faster way to diagnose hepatic encephalopathy than standard psychometric tests (average administration time of 15 minutes versus 37 minutes).[3]
References
- ↑ Ong JP, Aggarwal A, Krieger D, Easley KA, Karafa MT, Van Lente F; et al. (2003). "Correlation between ammonia levels and the severity of hepatic encephalopathy". Am J Med. 114 (3): 188–93. PMID 12637132.
- ↑ Sharma P, Sharma BC, Sarin SK (2009). "Predictors of nonresponse to lactulose for minimal hepatic encephalopathy in patients with cirrhosis". Liver Int. 29 (9): 1365–71. doi:10.1111/j.1478-3231.2009.02067.x. PMID 19555401.
- ↑ Bajaj JS, Saeian K, Verber MD; et al. (2007). "Inhibitory control test is a simple method to diagnose minimal hepatic encephalopathy and predict development of overt hepatic encephalopathy". Am. J. Gastroenterol. 102 (4): 754–60. doi:10.1111/j.1572-0241.2007.01048.x. PMID 17222319.