Graft-versus-host disease epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
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==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
GvHD affects 30*70% of patients who undergo allogeneic transplant.<ref name="pmid21130418">{{cite journal| author=Lee SJ| title=Have we made progress in the management of chronic graft-vs-host disease? | journal=Best Pract Res Clin Haematol | year= 2010 | volume= 23 | issue= 4 | pages= 529-35 | pmid=21130418 | doi=10.1016/j.beha.2010.09.016 | pmc=3053022 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21130418 }} </ref> It is not an uncommon complication of stem cell transplant. It tends to occur more often in patients who have less genetic similarity compared to their donors. It typically occurs within the first 100 days of transplant (acute GvHD) (approximately 90-95% of cases), though it can also occur after the 100-day time point (chronic GvHD). The median time of onset is approximately 5 months.<ref name="pmid21130418">{{cite journal| author=Lee SJ| title=Have we made progress in the management of chronic graft-vs-host disease? | journal=Best Pract Res Clin Haematol | year= 2010 | volume= 23 | issue= 4 | pages= 529-35 | pmid=21130418 | doi=10.1016/j.beha.2010.09.016 | pmc=3053022 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21130418 }} </ref> | |||
==References== | ==References== | ||
Revision as of 17:33, 14 June 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]
Overview
Epidemiology and Demographics
GvHD affects 30*70% of patients who undergo allogeneic transplant.[1] It is not an uncommon complication of stem cell transplant. It tends to occur more often in patients who have less genetic similarity compared to their donors. It typically occurs within the first 100 days of transplant (acute GvHD) (approximately 90-95% of cases), though it can also occur after the 100-day time point (chronic GvHD). The median time of onset is approximately 5 months.[1]
References
- ↑ 1.0 1.1 Lee SJ (2010). "Have we made progress in the management of chronic graft-vs-host disease?". Best Pract Res Clin Haematol. 23 (4): 529–35. doi:10.1016/j.beha.2010.09.016. PMC 3053022. PMID 21130418.