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:* Culture-directed antimicrobial therapy
:* Culture-directed antimicrobial therapy
::* Penicillin-susceptible strain
::* Penicillin-susceptible Staphylococcus aureus or Streptococcus
:::* Preferred regimen: [[Penicillin G]] 4 MU IV q4h for 2–4 weeks, then PO to complete 6–8 weeks
:::* Preferred regimen: [[Penicillin G]] 4 MU IV q4h for 2–4 weeks, then PO to complete 6–8 weeks


::* Oxacillin-susceptible strain
::* Oxacillin-susceptible Staphylococcus aureus or Streptococcus
:::* Preferred regimen: [[Cefazolin]] 2 g IV q8h for 2–4 weeks, then PO to complete 6–8 weeks {{or}} [[Nafcillin]] 2 g IV q4h for 2–4 weeks, then PO to complete 6–8 weeks {{or}} [[Oxacillin]] 2 g IV q4h for 2–4 weeks, then PO to complete 6–8 weeks
:::* Preferred regimen: [[Cefazolin]] 2 g IV q8h for 2–4 weeks, then PO to complete 6–8 weeks {{or}} [[Nafcillin]] 2 g IV q4h for 2–4 weeks, then PO to complete 6–8 weeks {{or}} [[Oxacillin]] 2 g IV q4h for 2–4 weeks, then PO to complete 6–8 weeks



Revision as of 20:04, 1 June 2015

Epidural abscess

  • Empiric antimicrobial therapy
  • Preferred regimen: Vancomycin 15 mg/kg IV q12h for 2–4 weeks, then PO to complete 6–8 weeks AND Ceftriaxone 2 g Iv q24h for 2–4 weeks, then PO to complete 6–8 weeks
Note (1): Decompressive laminectomy in conjunction with long-term antibiotic therapy tailored to culture results is required.
Note (2): For critically ill patients, a vancomycin loading dose of 20–25 mg/kg may be considered.
  • Culture-directed antimicrobial therapy
  • Penicillin-susceptible Staphylococcus aureus or Streptococcus
  • Preferred regimen: Penicillin G 4 MU IV q4h for 2–4 weeks, then PO to complete 6–8 weeks
  • Oxacillin-susceptible Staphylococcus aureus or Streptococcus
  • Preferred regimen: Cefazolin 2 g IV q8h for 2–4 weeks, then PO to complete 6–8 weeks OR Nafcillin 2 g IV q4h for 2–4 weeks, then PO to complete 6–8 weeks OR Oxacillin 2 g IV q4h for 2–4 weeks, then PO to complete 6–8 weeks

Brain abscess

  • Brain abscess, bacterial[3]
  • Empiric antimicrobial therapy


  • Brain abscess, tuberculous


  • Brain abscess, fungal

References

  1. Kasper, Dennis (2015). Harrison's principles of internal medicine. New York: McGraw Hill Education. ISBN 978-0071802154.
  2. Bartlett, John (2012). Johns Hopkins ABX guide : diagnosis and treatment of infectious diseases. Burlington, MA: Jones and Bartlett Learning. ISBN 978-1449625580.
  3. Bennett, John (2015). Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1455748013.