Heartburn causes: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Heartburn}} | {{Heartburn}} | ||
{{CMG}} {{AE}} {{ | {{CMG}} {{AE}} {{Jose}} | ||
==Overview== | ==Overview== | ||
[[Heartburn]] is commonly caused by [[gastroesophageal reflux disease]] ([[GERD]]) or adverse reactions to various food and drugs, causing [[esophagitis]]. | [[Heartburn]] is commonly caused by [[gastroesophageal reflux disease]] ([[GERD]]) or adverse reactions to various food and drugs, causing [[esophagitis]]. | ||
Life threatening causes of [[heartburn]] are far less common and include [[acute coronary syndromes]] and [[esophageal cancer]]. | Life threatening causes of [[heartburn]] are far less common and include [[acute coronary syndromes]] and [[esophageal cancer]]. | ||
==Causes== | ==Causes== | ||
===Life Threatening Causes=== | ===Life Threatening Causes=== | ||
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===Common Causes=== | ===Common Causes=== | ||
*[[Gastroesophageal reflux disease]] ([[GERD]]) | *[[Gastroesophageal reflux disease]] ([[GERD]])<ref name="pmid17345925">{{cite journal |vauthors=De Giorgi F, Palmiero M, Esposito I, Mosca F, Cuomo R |title=Pathophysiology of gastro-oesophageal reflux disease |journal=Acta Otorhinolaryngol Ital |volume=26 |issue=5 |pages=241–6 |date=October 2006 |pmid=17345925 |pmc=2639970 |doi= |url=}}</ref> | ||
*[[Esophagitis]] | *[[Esophagitis]] <ref name="pmid16926745">{{cite journal |vauthors=Fennerty MB, Johnson DA |title=Heartburn severity does not predict disease severity in patients with erosive esophagitis |journal=MedGenMed |volume=8 |issue=2 |pages=6 |date=April 2006 |pmid=16926745 |pmc=1785158 |doi= |url=}}</ref> | ||
*[[Hiatal hernia]]<ref name="pmid24917956">{{cite journal |vauthors=Karamanolis G, Polymeros D, Triantafyllou K, Adamopoulos A, Barbatzas C, Vafiadis I, Ladas SD |title=Hiatal hernia predisposes to nocturnal gastro-oesophageal reflux |journal=United European Gastroenterol J |volume=1 |issue=3 |pages=169–74 |date=June 2013 |pmid=24917956 |pmc=4040758 |doi=10.1177/2050640613490295 |url=}}</ref> | |||
*Motility disorders (e.g., [[gastroparesis]]) | *Motility disorders (e.g., [[gastroparesis]]) | ||
*[[Peptic ulcer]] disorder | *[[Peptic ulcer]] disorder | ||
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**[[Alpha-adrenergic antagonist]]s | **[[Alpha-adrenergic antagonist]]s | ||
**[[Anticholinergic]] agents | **[[Anticholinergic]] agents | ||
**[[Aspirin and other [[nonsteroidal anti-inflammatory drugs]] | **[[Aspirin]] and other [[nonsteroidal anti-inflammatory drugs]] | ||
**[[Beta2 -adrenergic drugs]] | **[[Beta2 -adrenergic drugs]] | ||
**[[Barbiturates]] | **[[Barbiturates]] | ||
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*Other: | *Other: | ||
**Genetics | **Genetics | ||
**Pregnancy | **Pregnancy<ref name="urlwww.worldgastroenterology.org">{{cite web |url=https://www.worldgastroenterology.org/UserFiles/file/WDHD-2015-handbook-final.pdf |title=www.worldgastroenterology.org |format= |work= |accessdate=}}</ref> | ||
==Less Common Causes== | ==Less Common Causes== | ||
*[[Scleroderma]] | *[[Scleroderma]] | ||
*[[Zollinger-Ellison syndrome]] | *[[Zollinger-Ellison syndrome]] | ||
*[[Pericarditis]] | |||
==References== | ==References== | ||
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[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Digestive disease symptoms]] | [[Category:Digestive disease symptoms]] | ||
[[Category:Up-To-Date]] |
Latest revision as of 15:10, 28 September 2020
Heartburn Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Heartburn causes On the Web |
American Roentgen Ray Society Images of Heartburn causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: José Eduardo Riceto Loyola Junior, M.D.[2]
Overview
Heartburn is commonly caused by gastroesophageal reflux disease (GERD) or adverse reactions to various food and drugs, causing esophagitis. Life threatening causes of heartburn are far less common and include acute coronary syndromes and esophageal cancer.
Causes
Life Threatening Causes
These causes present with chest pain that may present similarly to heartburn and also other clinical features that occur with heartburn:
Common Causes
- Gastroesophageal reflux disease (GERD)[1]
- Esophagitis [2]
- Hiatal hernia[3]
- Motility disorders (e.g., gastroparesis)
- Peptic ulcer disorder
- Lifestyle:
- Medications:
- Alpha-adrenergic antagonists
- Anticholinergic agents
- Aspirin and other nonsteroidal anti-inflammatory drugs
- Beta2 -adrenergic drugs
- Barbiturates
- Benzodiazepines
- Bisphosphonates
- Calcium channel blockers
- Chemotherapy
- Dopamine
- Estrogen
- Iron
- Narcotic analgesics
- Nitrates
- Potassium
- Progesterone
- Prostaglandins
- Quinidine
- Tetracycline
- Theophylline
- Tricyclic antidepressants
- Zidovudine
- Dietary:
- Alcohol
- Caffeinated beverages
- Carbonated beverages
- Chocolate
- Citrus fruit or juices
- Fatty foods
- Garlic or onions
- Mint (peppermint, spearmint)
- Salt and salt substitutes
- Spicy foods
- Tomatoes/tomato juice
- Other:
- Genetics
- Pregnancy[4]
Less Common Causes
References
- ↑ De Giorgi F, Palmiero M, Esposito I, Mosca F, Cuomo R (October 2006). "Pathophysiology of gastro-oesophageal reflux disease". Acta Otorhinolaryngol Ital. 26 (5): 241–6. PMC 2639970. PMID 17345925.
- ↑ Fennerty MB, Johnson DA (April 2006). "Heartburn severity does not predict disease severity in patients with erosive esophagitis". MedGenMed. 8 (2): 6. PMC 1785158. PMID 16926745.
- ↑ Karamanolis G, Polymeros D, Triantafyllou K, Adamopoulos A, Barbatzas C, Vafiadis I, Ladas SD (June 2013). "Hiatal hernia predisposes to nocturnal gastro-oesophageal reflux". United European Gastroenterol J. 1 (3): 169–74. doi:10.1177/2050640613490295. PMC 4040758. PMID 24917956.
- ↑ "www.worldgastroenterology.org" (PDF).