Hirschsprung's disease natural history, complications and prognosis: Difference between revisions

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{{Hirschsprung's disease}}
{{Hirschsprung's disease}}
{{CMG}};{{AE}}{{AY}}
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==Overview==
==Overview==
If left untreated, Hirschsprung disease can lead to [[enterocolitis]] and death. After proper surgical intervention, [[Mortality rate|mortality]] drops significantly. Common complications include [[enterocolitis]], [[intestinal perforation]] and [[short bowel syndrome]].
If left untreated, Hirschsprung's disease can lead to [[enterocolitis]] and even death. Common complications include [[enterocolitis]], [[intestinal perforation]], and [[short bowel syndrome]]. Using appropriate surgical interventions, [[Mortality rate|mortality rate]] drops significantly.  
==Natural history==
==Natural history==
If left untreated, Hirschsprung disease can lead to [[enterocolitis]] and death. After proper surgical intervention, mortality drops significantly.
If left untreated, Hirschsprung's disease can lead to [[enterocolitis]] and even death.  
==Complications==
==Complications==
* [[Inflammation]] and [[infection]] of the [[intestine]]s ([[enterocolitis]]).<ref name="pmid6712314">{{cite journal |vauthors=Ikeda K, Goto S |title=Diagnosis and treatment of Hirschsprung's disease in Japan. An analysis of 1628 patients |journal=Ann. Surg. |volume=199 |issue=4 |pages=400–5 |year=1984 |pmid=6712314 |pmc=1353357 |doi= |url=}}</ref>
* Intestinal perforation.
* [[Short bowel syndrome]], a condition that can lead to [[malnourishment]] and [[dehydration]].


===Possible complications of surgery include===
=== Possible complications of disease include: ===
*Wound infection
* [[Inflammation]] and [[infection]] of the [[intestine]]s/[[colon]] ([[enterocolitis]])
*[[Anastomotic lesions|Anastomotic leakage]]
* [[Intestinal perforation]]
* [[Short bowel syndrome]] (which can lead to [[malnourishment]] and [[dehydration]])<ref name="pmid6712314">{{cite journal |vauthors=Ikeda K, Goto S |title=Diagnosis and treatment of Hirschsprung's disease in Japan. An analysis of 1628 patients |journal=Ann. Surg. |volume=199 |issue=4 |pages=400–5 |year=1984 |pmid=6712314 |pmc=1353357 |doi= |url=}}</ref>
 
===Possible complications of reconstructive surgery include:===
*Wound [[infection]]
*[[Anastomotic lesions|Anastomosis leakage]]
*[[Intestinal obstruction]]
*[[Intestinal obstruction]]
*[[Pelvic abscess]]
*[[Pelvic abscess]]
*Chronic obstructive symptoms
*[[Chronic]] [[bowel obstruction]] symptoms
*Chronic [[constipation]] or [[diarrhea]]
*[[Chronic]] [[constipation]] or [[diarrhea]]<ref name="pmid6712314">{{cite journal |vauthors=Ikeda K, Goto S |title=Diagnosis and treatment of Hirschsprung's disease in Japan. An analysis of 1628 patients |journal=Ann. Surg. |volume=199 |issue=4 |pages=400–5 |year=1984 |pmid=6712314 |pmc=1353357 |doi= |url=}}</ref>


==Prognosis==
==Prognosis==
*Hirschsprung disease can lead to [[Mortality rate|mortality]] in up to 80% of the cases.  
*Hirschsprung's disease can lead to [[Mortality rate|mortality]] in up to 80% of cases.  
*After proper surgical intervention, [[Mortality rate|mortality]] drops to 30 %.
*Using appropriate surgical interventions, [[Mortality rate|mortality]] would drops to 30%.


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
[[Category:Needs content]]
[[Category:needs overview]]
[[Category:Disease]]
[[Category:Gastroenterology]]
[[Category:Congenital disorders]]

Latest revision as of 14:59, 21 August 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]

Overview

If left untreated, Hirschsprung's disease can lead to enterocolitis and even death. Common complications include enterocolitis, intestinal perforation, and short bowel syndrome. Using appropriate surgical interventions, mortality rate drops significantly.

Natural history

If left untreated, Hirschsprung's disease can lead to enterocolitis and even death.

Complications

Possible complications of disease include:

Possible complications of reconstructive surgery include:

Prognosis

  • Hirschsprung's disease can lead to mortality in up to 80% of cases.
  • Using appropriate surgical interventions, mortality would drops to 30%.

References

  1. 1.0 1.1 Ikeda K, Goto S (1984). "Diagnosis and treatment of Hirschsprung's disease in Japan. An analysis of 1628 patients". Ann. Surg. 199 (4): 400–5. PMC 1353357. PMID 6712314.