Hand-foot-and-mouth disease differential diagnosis: Difference between revisions
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[[Image:Home_logo1.png|right|250px|link=https://www.wikidoc.org/index.php/Hand-foot-and-mouth_disease]] | |||
{{CMG}} {{AE}} {{AN}} | {{CMG}} {{AE}} {{AN}}, {{YK}}, {{AKI}} | ||
==Overview== | ==Overview== | ||
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* [[Herpes simplex virus]] infections | * [[Herpes simplex virus]] infections | ||
* [[Herpangina]] | * [[Herpangina]] | ||
* [[Chicken pox]] | * [[Chicken pox]] | ||
* [[Measles]] | * [[Measles]] | ||
* [[Aphthous ulcers]]/ [[Gingivitis]] | * [[Aphthous ulcers]]/ [[Gingivitis]] | ||
** The [[ulcer]]s are on the mucosal surface of the mouth and is not associated with [[fever]], [[malaise]] or [[rash]]. | ** The [[ulcer]]s are on the mucosal surface of the mouth and is not associated with [[fever]], [[malaise]] or [[rash]]. | ||
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*Sudden [[fever]] | *Sudden [[fever]] | ||
*[[Sore throat]] and [[dysphagia]]- These can occur several hours(up to 24 hours), before the appearance of the | *[[Sore throat]] and [[dysphagia]]- These can occur several hours(up to 24 hours), before the appearance of the enanthem. | ||
*[[Vomiting]] | *[[Vomiting]] | ||
*[[Abdominal pain]] | *[[Abdominal pain]] | ||
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*Oral Cavity | *Oral Cavity | ||
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*Characteristic | *Characteristic enanthem- Punctate [[macule]] which evolve over a period of 24 hours to 2-4mm erythematous papules which vesiculate, and then centrally ulcerate. | ||
*The lesions are usually small in number, and evolve rapidly. The lesions are seen more commonly on the [[soft palate]] and [[uvula]]. The lesions can also be seen on the [[tonsils]], posterior pharyngeal wall and the [[buccal mucosa]]. | *The lesions are usually small in number, and evolve rapidly. The lesions are seen more commonly on the [[soft palate]] and [[uvula]]. The lesions can also be seen on the [[tonsils]], posterior pharyngeal wall and the [[buccal mucosa]]. | ||
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[[File: | [[File:Herpangina3.jpg|center|400x400px|alt=Erythema, vesicles and ulcerating lesions in herpangina|Erythema, vesicles and ulcerating lesions in herpangina]] | ||
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|Primary herpetic gingivoestomatitis<ref name="KolokotronisDoumas2006">{{cite journal|last1=Kolokotronis|first1=A.|last2=Doumas|first2=S.|title=Herpes simplex virus infection, with particular reference to the progression and complications of primary herpetic gingivostomatitis|journal=Clinical Microbiology and Infection|volume=12|issue=3|year=2006|pages=202–211|issn=1198743X|doi=10.1111/j.1469-0691.2005.01336.x}}</ref> | |Primary herpetic gingivoestomatitis<ref name="KolokotronisDoumas2006">{{cite journal|last1=Kolokotronis|first1=A.|last2=Doumas|first2=S.|title=Herpes simplex virus infection, with particular reference to the progression and complications of primary herpetic gingivostomatitis|journal=Clinical Microbiology and Infection|volume=12|issue=3|year=2006|pages=202–211|issn=1198743X|doi=10.1111/j.1469-0691.2005.01336.x}}</ref> | ||
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*Ulcers are common on lips, gums, throat, front of tongue, inside of the cheeks and roof of the mouth | *Ulcers are common on lips, gums, throat, front of tongue, inside of the cheeks and roof of the mouth | ||
*Treatment is with antiviral agents such as [[Valacyclovir]] and [[Famciclovir]] | *Treatment is with antiviral agents such as [[Valacyclovir]] and [[Famciclovir]] | ||
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[[File:Herpes labialis - opryszczka wargowa.jpg|400x400px]] | |||
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{{WH}} | {{WH}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
[[Category:Pediatrics]] | [[Category:Pediatrics]] | ||
[[Category:Viral diseases]] | [[Category:Viral diseases]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Emergency mdicine]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Infectious disease]] | [[Category:Infectious disease]] | ||
[[Category:Dermatology]] | |||
[[Category:Otolaryngology]] |
Latest revision as of 21:56, 29 July 2020
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2], Yamuna Kondapally, M.B.B.S[3], Aravind Kuchkuntla, M.B.B.S[4]
Overview
Hand-foot-and-mouth disease should be differentiated from other conditions that cause maculopapular or vesicular rash which includes herpes simplex virus infections, herpangina, chicken pox and measles.
Differentiating Hand-foot-and-mouth disease from other Diseases
Hand-foot-and-mouth disease should be differentiated from other conditions that cause maculopapular or vesicular rash include:
- Herpes simplex virus infections
- Herpangina
- Chicken pox
- Measles
- Aphthous ulcers/ Gingivitis
- Stevens-Johnson syndrome/ Erythema multiforme
- Henoch-Schönlein purpura
- Kawasaki disease
- Other rare conditions in children:
The following table is a list of differential diagnosis and their features:
Disease | Presentation | Risk Factors | Diagnosis | Affected Organ Systems | Important features | Picture |
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Coxsackie virus |
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Chicken pox |
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Measles |
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Herpangina |
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Primary herpetic gingivoestomatitis[3] |
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References
- ↑ Feikin DR, Lezotte DC, Hamman RF, Salmon DA, Chen RT, Hoffman RE (2000). "Individual and community risks of measles and pertussis associated with personal exemptions to immunization". JAMA. 284 (24): 3145–50. PMID 11135778.
- ↑ Ratnam S, West R, Gadag V, Williams B, Oates E (1996). "Immunity against measles in school-aged children: implications for measles revaccination strategies". Can J Public Health. 87 (6): 407–10. PMID 9009400.
- ↑ Kolokotronis, A.; Doumas, S. (2006). "Herpes simplex virus infection, with particular reference to the progression and complications of primary herpetic gingivostomatitis". Clinical Microbiology and Infection. 12 (3): 202–211. doi:10.1111/j.1469-0691.2005.01336.x. ISSN 1198-743X.
- ↑ Chauvin PJ, Ajar AH (2002). "Acute herpetic gingivostomatitis in adults: a review of 13 cases, including diagnosis and management". J Can Dent Assoc. 68 (4): 247–51. PMID 12626280.