Phyllodes tumor: Difference between revisions

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__NOTOC__
#REDIRECT [[Breast cancer]]
{{SI}}                                                                     
{{CMG}} {{AE}} {{MV}}
{{SK}} Cystosarcoma phyllodes;
==Overview==
 
'''Phyllodes tumor''' (also known as ''cystosarcoma phyllodes''), is a typically large, fast-growing mass that arises from the periductal [[stromal cell]]s of the [[breast]]. Phyllodes tumors account for less than 1% of all breast [[Neoplasia|neoplasms]].
 
==Historical Perspective==
*Phyllodes tumor was first discovered by [scientist name], a [nationality + occupation], in [year] during/following [event].
 
==Classification==
*Phyllodes tumor may be classified according to [classification method] into [number] subtypes/groups:
:*[group1]
:*[group2]
:*[group3]
*Other variants of phyllodes tumor include [disease subtype 1], [disease subtype 2], and [disease subtype 3].
==Pathophysiology==
*The pathogenesis of phyllodes tumor is characterized by [feature1], [feature2], and [feature3].
*Genes involved in the development of phyllodes tumor, include:
*On gross pathology, characteristic findings of phyllodes tumor, include:
:*Cleft/leaf-like structures
:*Friable mass
:*Well-defined margins
*On microscopic histopathological analysis,characteristic findings of phyllodes tumor, include:
:*Large slit-like spaces
:*Cellular myxoid stroma
:*+/-Infiltrative border
:*Stromal overgrowth
 
==Causes==
* There are no established causes for phyllodes tumor.
 
==Differentiating Phyllodes Tumor from Other Diseases==
*Phyllodes tumor must be differentiated from other diseases that cause a breast mass, such as:
:*[Differential dx1]
:*[Differential dx2]
:*[Differential dx3]
 
==Epidemiology and Demographics==
* The prevalence of phyllodes tumor is approximately [number or range] per 100,000 individuals worldwide.
* In [year], the incidence of phyllodes tumor was estimated to be [number or range] cases per 100,000 individuals in [location].
===Age===
*Patients of all age groups may develop phyllodes tumor.
===Gender===
*Females are more commonly affected with phyllodes tumor than males. 
===Race===
*There is no racial predilection for phyllodes tumor.
 
==Risk Factors==
*Common risk factors in the development of phyllodes tumor, include:
 
== Natural History, Complications and Prognosis==
*The majority of patients with phyllodes tumor remain asymptomatic for [duration/years].
*Early clinical features include [manifestation 1], [manifestation 2], and [manifestation 3].
*If left untreated, [#%] of patients with phyllodes tumor may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
*Common complications of phyllodes tumor include [complication 1], [complication 2], and [complication 3].
*Prognosis is generally [excellent/good/poor], and the [1/5/10­year mortality/survival rate] of patients with phyllodes tumor is approximately [#%].
== Diagnosis ==
===Diagnostic Criteria===
*The diagnosis of phyllodes tumor is made with biopsy.
=== Symptoms ===
*Phyllodes tumor is usually asymptomatic.
*Symptoms of phyllodes tumor may include the following:
:*[symptom 1]
:*[symptom 2]
:*[symptom 3]
:*[symptom 4]
:*[symptom 5]
:*[symptom 6]
=== Physical Examination ===
*Patients with phyllodes tumor usually appear [general appearance].
*Physical examination may be remarkable for:
:*[finding 1]
:*[finding 2]
:*[finding 3]
:*[finding 4]
:*[finding 5]
:*[finding 6]
=== Laboratory Findings ===
*There are no specific laboratory findings associated with phyllodes tumor.
 
*A  [positive/negative] [test name] is diagnostic of phyllodes tumor.
*An [elevated/reduced] concentration of [serum/blood/urinary/CSF/other] [lab test] is diagnostic of phyllodes tumor.
*Other laboratory findings consistent with the diagnosis of phyllodes tumor include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
===Imaging Findings===
*[Imaging study 1] is the imaging modality of choice for phyllodes tumor.
*On [imaging study 1], findings of phyllodes tumor include:
 
== Treatment ==
=== Medical Therapy ===
*The mainstay of therapy for phyllodes tumor is [medical therapy 1] and [medical therapy 2].
 
=== Surgery ===
*Surgery is the mainstay of therapy for phyllodes tumor.
*[Surgical procedure] in conjunction with [chemotherapy/radiation] is the most common approach to the treatment of phyllodes tumor.
*[Surgical procedure] can only be performed for patients with [disease stage] phyllodes tumor.
=== Prevention ===
*Effective measures for the primary prevention of phyllodes tumor include periodical self-breast examination, and routine mammography. 
*Once diagnosed and successfully treated, patients with phyllodes tumor are followed-up periodically.
*Follow-up testing, includes: ultrasound examination.
 
==References==
{{Reflist|2}}
[[Category:Oncology]]

Latest revision as of 17:56, 12 March 2019

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