Liposarcoma risk factors: Difference between revisions
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==Overview== | ==Overview== | ||
Common risk factors in the development of liposarcoma include [[chemical]] [[Carcinogen|carcinogens]], [[radiation]], [[immunodeficiency]], [[genetic disorders]], and [[Viral infection|viral infections]]. | |||
==== | ==Risk Factors== | ||
Common [[Risk factor|risk factors]] in the development of liposarcoma are:<ref name="WHO-SOft">{{cite web | title = WHO-Soft tissue tumor | url = http://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb5/bb5-classifsofttissue.pdf }}</ref><ref name="WHO-SOft">{{cite web | title = WHO-Soft tissue tumor | url = http://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb5/bb5-classifsofttissue.pdf }}</ref> | |||
*[[Chemical]] [[Carcinogen|carcinogens]] | |||
**[[Herbicide|Phenoxyacetic herbicides]] | |||
**Chlorophenols | |||
**[[Dioxin]] [[contamination]] | |||
**[[Arsenic]] | |||
**[[Thorium dioxide|Thorium dioxide (Thorotrast)]] | |||
*[[Radiation]] | |||
**Risk is associated with [[adjuvant therapy]] of [[radiation]] for [[breast carcinoma]]. | |||
**Risk increases with [[dose]] and a [[dose]] of 50 GY or more of [[radiation]] has been recorded with increased risk of [[sarcoma]]. | |||
**The [[mean]] period between exposure to [[Radiation therapy|radiation]] and [[tumor]] [[diagnosis]] is 10 years. | |||
*[[Immunodeficiency]] | |||
**Regional acquired [[immunodeficiency]] is sometimes associated with liposarcoma. | |||
*[[Genetic]] susceptibility | |||
**[[Li-Fraumeni syndrome]] | |||
**[[Neurofibromatosis|Neurofibromatosis (NF1; von Recklinghausen disease)]] | |||
**[[Gardner syndrome|Gardner syndrome (Familial adenomatous polyposis)]] | |||
**[[Retinoblastoma]] | |||
**[[Werner syndrome]] | |||
**[[Basal cell carcinoma|Nevoid basal cell carcinoma (Gorlin syndrome)]] | |||
*[[Viral infection|Viral infections]] | |||
==References== | ==References== | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Surgery]] | [[Category:Surgery]] | ||
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Latest revision as of 16:08, 24 May 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Common risk factors in the development of liposarcoma include chemical carcinogens, radiation, immunodeficiency, genetic disorders, and viral infections.
Risk Factors
Common risk factors in the development of liposarcoma are:[1][1]
- Immunodeficiency
- Regional acquired immunodeficiency is sometimes associated with liposarcoma.
- Genetic susceptibility
References
- ↑ 1.0 1.1 "WHO-Soft tissue tumor" (PDF).