Alpha-4 beta-2 nicotinic receptor: Difference between revisions
Jump to navigation
Jump to search
m (Bot: Automated text replacement (-{{SIB}} + & -{{EH}} + & -{{EJ}} + & -{{Editor Help}} + & -{{Editor Join}} +)) |
(No difference)
|
Revision as of 20:55, 8 August 2012
Overview
The alpha-4 beta-2 nicotinic receptor ((α4)2(β2)3) is a type of nicotinic acetylcholine receptor, consisting of α4 and β2 subunits[1].
It is located in the brain, where activation yields post- and presynaptic excitation[1], mainly by increased Na+ and K+ permeability.
Agonists
Nicotinic agonists for this receptor include:
Antagonists
- mecamylamine
- methylaconitine
- α-conotoxin