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! align="center" style="background: #4479BA; color: #FFFFFF |Patient
! align="center" style="background: #4479BA; color: #FFFFFF |Disease name


! align="center" style="background: #4479BA; color: #FFFFFF |Symptoms
! align="center" style="background: #4479BA; color: #FFFFFF |Symptoms


! align="center" style="background: #4479BA; color: #FFFFFF |Past medical history and risk factors
! align="center" style="background: #4479BA; color: #FFFFFF |Laboratory findings


! align="center" style="background: #4479BA; color: #FFFFFF |Laboratory findings


! align="center" style="background: #4479BA; color: #FFFFFF |Treatment


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| 55 year old, male admitted due
| Alzheimer's disease
to


* fever,  
| Chronic, gradually progressive neurodegenerative disease.  
* cough
* shortness of breath with suspected [[COVID-19]].


| Developed [[chest pain]] 48 hrs after admission
* Slow onset of dementia,
* No motor, sensory or deficits in co ordination early in the disease


|[[Peripheral arterial disease|Peripheral artery disease]]
|On CSF exam:


|
* Elevated Tau protein
* [[The electrocardiogram|EKG]]:  Inferior leads shows Inverted T waves.
*[[Troponin I]]<nowiki> : Elevated (355 ng/l --->70 ng/l 3 h later )[normal values <7 ng/l)]</nowiki>


* [[Transthoracic echocardiography]]:
[[Neurofibrillary tangle|Neurofibrillary tangles]]
**Left ventricular [[ejection fraction]] :60%
**No abnormalities in wall motion.
**Absence of [[Diastole|diastolic]] dysfunction
**Presence of mild [[mitral regurgitation]]


* [[Coronary angiography|Coronary angiogram]] : posterior
[[Senile plaques|Senile (neuritic) plaques]]


descending artery is occluded with [[epicardial]] collateral from the left anterior descending artery.
|-


In tmid-right coronary artery, an intimal tear is present with a spontaneous dissecting coronary [[hematoma]] 
|Lewy Body Dementia


* Optical coherence tomography ([[Cardiac Optical Coherence Tomography (OCT)|OCT]]): spontaneous dissecting coronary [[hematoma]] with an intimal rupture of right coronary artery
|
* Dementia with cognitive impairment
* Visual hallucinations
 
* Parkinsonism


|
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*[[Aspirin]], [[Statins]], and [[Beta blockers|Beta-blockers]].


* Coronary angiogram was planned.
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|Frontotemporal Dementia
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|Vasculitis
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|Hashi moto encephalopathy
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|Electrolyte Imbalance
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|Vitamin B1 deficiency
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|Wilson's disease
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|Heavy metal intoxication
|70-year-old, male
|
 
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|Severe , persistent chest pain ( 8/10), which started 3 hrs before admission
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|Hepatic Encephalopathy
|Smoking, [[Hypertension]], and Type 2 diabetes,
|
 
|-
H/O  [[percutaneous coronary intervention]] (PCI) with implantation of a [[Drug eluting stent|drug-eluting stent]] (DES)
|HIV- related mental status change
 
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|Lyme disease
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|Syphilis
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|CNS malignancy
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|Psychiatric conditions
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* EKG: [[Precordium|precordial]] leads shows new ST-T abnormalities which was not present previously.
[[Image:70yr.png|thumb|700px|right|frame|ST-T abnormalities in the precordial leads.]]
* [[Echocardiography|Echocardiogram]]:
**Left ventricular [[ejection fraction]]  40–45% with [[akinesia]] in the LCx territory (old) and
**a severe [[Hypokinesia|hypokinesis]] in the left anterior ascending (LAD).
* [[Coronary angiography|Coronary angiogram]]: moderate in-stent restenosis present on LCx-OM and a moderate right coronary artery (RCA) stenosis
|
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*[[Heparin]], [[Nitroglycerin (Sublingual tablet)|Sublingual nitroglycerin]], and [[Clopidogrel]]
* Angiogram was performed
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|Paraneoplastic limbic encephalitis
|48‐year‐old, female
|History of severe chest pain that awoke her from sleep,9/10,severe,retrosternal tightness,pain radiates to neck and both arms.
 
|[[Migraine]] and [[Hyperlipidemia]]
 
|
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* Elevated Troponin I from  <0.01 to  0.5 ng/ml (Normal: <0.80 ng/ml)
* [[Electrocardiogram]]: No  changes or signs of ischemia
* [[Echocardiogram|Transthoracic echocardiogram]] : Left ventricular [[ejection fraction]] 45–50% and  distal anteroseptal and apical segments shows akinesia
* [[Angiogram|Computed tomography coronary angiogram]]:mid‐to‐distal LAD dissected
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* Aspirin, [[Nitroglycerin (Sublingual tablet)|Sublingual nitroglycerin]]
|}
|}
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Latest revision as of 15:10, 31 July 2020

  • Here is a table presenting symptoms of the reported cases:
Disease name Symptoms Laboratory findings


Alzheimer's disease Chronic, gradually progressive neurodegenerative disease.
  • Slow onset of dementia,
  • No motor, sensory or deficits in co ordination early in the disease
On CSF exam:
  • Elevated Tau protein

Neurofibrillary tangles

Senile (neuritic) plaques

Lewy Body Dementia
  • Dementia with cognitive impairment
  • Visual hallucinations
  • Parkinsonism
Frontotemporal Dementia
Vasculitis
Hashi moto encephalopathy
Electrolyte Imbalance
Vitamin B1 deficiency
Wilson's disease
Heavy metal intoxication
Hepatic Encephalopathy
HIV- related mental status change
Lyme disease
Syphilis
CNS malignancy
Psychiatric conditions
Paraneoplastic limbic encephalitis