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= Acinic Cell Carcinoma Risk Factors=
__NOTOC__
{{Swathi}}
{{Acinic cell carcinoma}}


*Radiation exposure: Radiation treatment for the head and neck cancer increases the risk of developing salivary gland cancer. Workplace exposure to certain radioactive substances may also increase the risk of salivary gland cancer.  <ref name="Al-ZaherObeid2009">{{cite journal|last1=Al-Zaher|first1=Nabil|last2=Obeid|first2=Amani|last3=Al-Salam|first3=Suhail|last4=Al-Kayyali|first4=Bassam Sulaiman|title=Acinic cell carcinoma of the salivary glands: A literature review|journal=Hematology/Oncology and Stem Cell Therapy|volume=2|issue=1|year=2009|pages=259–264|issn=16583876|doi=10.1016/S1658-3876(09)50035-0}}</ref>
{{CMG}}; {{AE}} {{RG}}
*Therapeutic radiation of the head and neck region
==Overview==
*Positive family history: familial predisposition
 
*Strong association between Epstein Barr Virus and lymphoepithelial carcinomas
There is very little approved information about acinic cell carcinoma risk factors but Familial predisposition Previous radiation exposure may play an important role.
*Endogenous hormones: Estrogen receptors, progesterone receptors and androgen receptors
 
*Iodine treatment of thyroid disease
==Risk Factors==
*Occupational hazards:
Common risk factors in the development of acinic cell carcinoma include:
**Asbestos and rubber manufacturing
===Common Risk Factors===
**Exposure to metal in the plumbing industry
*Common risk factors in the development of acinic cell carcinoma may be occupational, environmental, genetic<ref name="pmid9118025">{{cite journal| author=Saku T, Hayashi Y, Takahara O, Matsuura H, Tokunaga M, Tokunaga M et al.| title=Salivary gland tumors among atomic bomb survivors, 1950-1987. | journal=Cancer | year= 1997 | volume= 79 | issue= 8 | pages= 1465-75 | pmid=9118025 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9118025  }}</ref><ref name="pmid10539921">{{cite journal| author=Depowski PL, Setzen G, Chui A, Koltai PJ, Dollar J, Ross JS| title=Familial occurrence of acinic cell carcinoma of the parotid gland. | journal=Arch Pathol Lab Med | year= 1999 | volume= 123 | issue= 11 | pages= 1118-20 | pmid=10539921 | doi=10.1043/0003-9985(1999)123<1118:FOOACC>2.0.CO;2 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10539921 }}</ref><ref name="VilleneuveTremblay2011">{{cite journal|last1=Villeneuve|first1=Hugo|last2=Tremblay|first2=Steve|last3=Galiatsatos|first3=Polymnia|last4=Hamel|first4=Nancy|last5=Guertin|first5=Louis|last6=Morency|first6=Renald|last7=Tischkowitz|first7=Marc|title=Acinic cell carcinoma of the retromolar trigone region: expanding the tumor phenotype in Cowden syndrome?|journal=Familial Cancer|volume=10|issue=4|year=2011|pages=691–694|issn=1389-9600|doi=10.1007/s10689-011-9472-8}}</ref>.
**Exposure to nickel compounds
*Common risk factors in the development of acinic cell carcinoma include:
**Woodworking in the automobile industry
**Familial predisposition
**Employment in hairdressing and beauty shops
**Previous radiation exposure
**[[Cowden syndrome]]
**Acinic breast cancer may develop in a [[BRCA1]] mutation carrier
**There were no cases among long-term atomic bomb survivors
 
==References==
{{Reflist|2}}
 
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Latest revision as of 03:43, 9 October 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2]

Overview

There is very little approved information about acinic cell carcinoma risk factors but Familial predisposition Previous radiation exposure may play an important role.

Risk Factors

Common risk factors in the development of acinic cell carcinoma include:

Common Risk Factors

  • Common risk factors in the development of acinic cell carcinoma may be occupational, environmental, genetic[1][2][3].
  • Common risk factors in the development of acinic cell carcinoma include:
    • Familial predisposition
    • Previous radiation exposure
    • Cowden syndrome
    • Acinic breast cancer may develop in a BRCA1 mutation carrier
    • There were no cases among long-term atomic bomb survivors

References

  1. Saku T, Hayashi Y, Takahara O, Matsuura H, Tokunaga M, Tokunaga M; et al. (1997). "Salivary gland tumors among atomic bomb survivors, 1950-1987". Cancer. 79 (8): 1465–75. PMID 9118025.
  2. Depowski PL, Setzen G, Chui A, Koltai PJ, Dollar J, Ross JS (1999). "Familial occurrence of acinic cell carcinoma of the parotid gland". Arch Pathol Lab Med. 123 (11): 1118–20. doi:10.1043/0003-9985(1999)123<1118:FOOACC>2.0.CO;2. PMID 10539921.
  3. Villeneuve, Hugo; Tremblay, Steve; Galiatsatos, Polymnia; Hamel, Nancy; Guertin, Louis; Morency, Renald; Tischkowitz, Marc (2011). "Acinic cell carcinoma of the retromolar trigone region: expanding the tumor phenotype in Cowden syndrome?". Familial Cancer. 10 (4): 691–694. doi:10.1007/s10689-011-9472-8. ISSN 1389-9600.

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