Parkinson's disease historical perspective: Difference between revisions
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{{Parkinson's disease}} | {{Parkinson's disease}} | ||
{{CMG}} | {{CMG}} {{AE}} {{Fs}} | ||
==Overview== | ==Overview== | ||
Parkinson disease was first documented and recognized by a British physician, [[James Parkinson]] in 1817 who named it paralysis agitans. The first underlying [[pathology]] of Parkinson disease was described by a German [[pathologist]] Frederick Lewy in 1912. He described that there are [[cytoplasmic]] [[inclusions]] in some [[brain]] areas of [[Parkinson's disease|PD]] patients. in 1967 the drug “[[L-dopa]]” was introduced to the market as a treatment of Parkinson ’s disease. | |||
==Historical Perspective== | ==Historical Perspective== | ||
=== Discovery === | |||
* Parkinson disease was first documented and recognized by a British physician, [[James Parkinson]] in 1817 who named it paralysis agitans.<ref name="Goetz2011">{{cite journal|last1=Goetz|first1=C. G.|title=The History of Parkinson's Disease: Early Clinical Descriptions and Neurological Therapies|journal=Cold Spring Harbor Perspectives in Medicine|volume=1|issue=1|year=2011|pages=a008862–a008862|issn=2157-1422|doi=10.1101/cshperspect.a008862}}</ref> | |||
* The current name of the disease (Parkinson disease) is from [[Jean-Martin Charcot]].<ref name="TeiveMunhoz2007">{{cite journal|last1=Teive|first1=Helio A. G.|last2=Munhoz|first2=Renato Puppi|last3=Barbosa|first3=Egberto Reis|title=Little-known scientific contributions of J-M Charcot|journal=Clinics|volume=62|issue=3|year=2007|pages=211–214|issn=1807-5932|doi=10.1590/S1807-59322007000300003}}</ref> | |||
* The first underlying [[pathology]] of Parkinson disease was described by a German [[pathologist]] Frederick Lewy in 1912. He described that there are [[cytoplasmic]] [[inclusions]] in some [[brain]] areas of [[Parkinson's disease|PD]] patients.<ref name="Goetz2011" /> | |||
* Later on in 1919 Tretiakoff showed that in this patients’ [[substantia nigra]] there are evidences of neuronal loss. | |||
* Finally in the 1950s [[dopamine]] depletion was known to be the underlying [[Causes|cause]] of the disease.<ref name="pmid17017502">{{cite journal |vauthors=Hornykiewicz O |title=The discovery of dopamine deficiency in the parkinsonian brain |journal=J. Neural Transm. Suppl. |volume= |issue=70 |pages=9–15 |date=2006 |pmid=17017502 |doi= |url=}}</ref> | |||
* Later, in 1967 the drug “[[L-dopa]]” was introduced to the market as a treatment of Parkinson ’s disease.<ref name="pmid10410773">{{cite journal |vauthors=Manyam BV, Sánchez-Ramos JR |title=Traditional and complementary therapies in Parkinson's disease |journal=Adv Neurol |volume=80 |issue= |pages=565–74 |date=1999 |pmid=10410773 |doi= |url=}}</ref><ref name="pmid11983801">{{cite journal |vauthors=Parkinson J |title=An essay on the shaking palsy. 1817 |journal=J Neuropsychiatry Clin Neurosci |volume=14 |issue=2 |pages=223–36; discussion 222 |date=2002 |pmid=11983801 |doi=10.1176/jnp.14.2.223 |url=}}</ref><ref name="pmid12373520">{{cite journal |vauthors=Hornykiewicz O |title=L-DOPA: from a biologically inactive amino acid to a successful therapeutic agent |journal=Amino Acids |volume=23 |issue=1-3 |pages=65–70 |date=2002 |pmid=12373520 |doi=10.1007/s00726-001-0111-9 |url=}}<nowiki><ref name="pmid5637779"></nowiki>{{cite journal |vauthors=Cotzias GC |title=L-Dopa for Parkinsonism |journal=N. Engl. J. Med. |volume=278 |issue=11 |pages=630 |date=March 1968 |pmid=5637779 |doi= |url=}}</ref> | |||
===Landmark Events in the Development of Treatment Strategies=== | |||
== References == | == References == | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Latest revision as of 13:38, 13 August 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.
Overview
Parkinson disease was first documented and recognized by a British physician, James Parkinson in 1817 who named it paralysis agitans. The first underlying pathology of Parkinson disease was described by a German pathologist Frederick Lewy in 1912. He described that there are cytoplasmic inclusions in some brain areas of PD patients. in 1967 the drug “L-dopa” was introduced to the market as a treatment of Parkinson ’s disease.
Historical Perspective
Discovery
- Parkinson disease was first documented and recognized by a British physician, James Parkinson in 1817 who named it paralysis agitans.[1]
- The current name of the disease (Parkinson disease) is from Jean-Martin Charcot.[2]
- The first underlying pathology of Parkinson disease was described by a German pathologist Frederick Lewy in 1912. He described that there are cytoplasmic inclusions in some brain areas of PD patients.[1]
- Later on in 1919 Tretiakoff showed that in this patients’ substantia nigra there are evidences of neuronal loss.
- Finally in the 1950s dopamine depletion was known to be the underlying cause of the disease.[3]
- Later, in 1967 the drug “L-dopa” was introduced to the market as a treatment of Parkinson ’s disease.[4][5][6]
Landmark Events in the Development of Treatment Strategies
References
- ↑ 1.0 1.1 Goetz, C. G. (2011). "The History of Parkinson's Disease: Early Clinical Descriptions and Neurological Therapies". Cold Spring Harbor Perspectives in Medicine. 1 (1): a008862–a008862. doi:10.1101/cshperspect.a008862. ISSN 2157-1422.
- ↑ Teive, Helio A. G.; Munhoz, Renato Puppi; Barbosa, Egberto Reis (2007). "Little-known scientific contributions of J-M Charcot". Clinics. 62 (3): 211–214. doi:10.1590/S1807-59322007000300003. ISSN 1807-5932.
- ↑ Hornykiewicz O (2006). "The discovery of dopamine deficiency in the parkinsonian brain". J. Neural Transm. Suppl. (70): 9–15. PMID 17017502.
- ↑ Manyam BV, Sánchez-Ramos JR (1999). "Traditional and complementary therapies in Parkinson's disease". Adv Neurol. 80: 565–74. PMID 10410773.
- ↑ Parkinson J (2002). "An essay on the shaking palsy. 1817". J Neuropsychiatry Clin Neurosci. 14 (2): 223–36, discussion 222. doi:10.1176/jnp.14.2.223. PMID 11983801.
- ↑ Hornykiewicz O (2002). "L-DOPA: from a biologically inactive amino acid to a successful therapeutic agent". Amino Acids. 23 (1–3): 65–70. doi:10.1007/s00726-001-0111-9. PMID 12373520.<ref name="pmid5637779">Cotzias GC (March 1968). "L-Dopa for Parkinsonism". N. Engl. J. Med. 278 (11): 630. PMID 5637779.