Granulosa cell tumour: Difference between revisions

Jump to navigation Jump to search
No edit summary
Tag: New redirect
 
(16 intermediate revisions by 6 users not shown)
Line 1: Line 1:
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
#REDIRECT [[Sexcord/ stromal ovarian tumors]]
 
{{DiseaseDisorder infobox |
  Name          = Granulosa cell tumour |
  ICD10          = {{ICD10|C|56||c|51}} |
  ICD9          = {{ICD9|183}} |
  ICDO          = 8620 |
  Image          = |
  Caption        = |
  OMIM          = |
  MedlinePlus    = |
  DiseasesDB    = |
}}
{{SI}}
{{EH}}
 
==Overview==
'''Granulosa cell tumours''' (or '''granulosa-theca''') are part of the [[sex cord-stromal tumour]] group of [[Ovarian cancer|ovarian neoplasm]]s.
 
The peak age at which they occur is 50-55 years, but they may occur at any age.
 
==Clinical presentation==
[[Estrogen]]s are produced by ''functioning'' tumours, and the clinical presentation depends on the patient's age.
* If the patient is [[postmenopausal]], she usually presents with [[abnormal uterine bleeding]].
* If the patient is of reproductive age, she would present with [[menometrorrhagia]].
* If the patient has not undergone [[puberty]], isosexual-pseudo-precocity may be seen.
 
==Histology==
The most characteristic gross appearance is a smooth surfaced solid and cystic lesion with the cysts filled with [[blood]].
Hemoperitoneum is an infrequent but classical presentation.
A large variety of [[histology|histological]] presentations exists, but they have two key features:
#[[Call-Exner bodies]] ([[granulosa cell]]s arranged haphazardly around a space containing [[eosinophilic]] fluid); ''and''
#Pale uniform nuclei, often with grooves
 
==See also==
* [[granulosa cell]]
* [[Sertoli-Leydig cell tumour]]
 
==External links==
* {{GPnotebook|-46858173}}
* [http://www-medlib.med.utah.edu/WebPath/FEMHTML/FEM057.html Photo of tumor]
* [http://www.bioscience.org/atlases/tumpath/freprod/ovary/9/micro.htm Slides]
* [http://www.indiandoctors.com/OBGYN/Malignancy/Malignancy_02.htm indiandoctors.com]
 
{{Epithelial neoplasms}}
{{SIB}}
[[Category:Gynecology]]
[[Category:Types of cancer]]
[[Category:Oncology]]
[[Category:Mature chapter]]
 
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}

Latest revision as of 15:08, 31 May 2019