Leiomyosarcoma history and symptoms: Difference between revisions

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{{Leiomyosarcoma}}
{{Leiomyosarcoma}}
{{CMG}}
{{CMG}}{{AE}}{{Nnasiri}}


== Overview ==
== Overview ==
The majority of patients with leiomyosarcoma remain asymptomatic for decades. General symptoms associated with cancer may occur including fatigue, fever, weight loss, a general feeling of ill health (malaise), and nausea and vomiting.
The majority of [[patients]] with [[leiomyosarcoma]] remain asymptomatic for decades. General [[symptoms]] associated with cancer may occur including [[fatigue]], [[fever]], [[weight loss]], [[nausea]] and [[vomiting]], [[vaginal bleeding]], [[vaginal discharge]], feeling of pressure in [[abdomen]] or [[pelvic]], painless growing [[lump]] in abdomen or [[pelvic cavity]].  


==History and Symptoms==
==History and Symptoms==
The symptoms of leiomyosarcoma depend on the location of the tumor. For the tumors always develope in gastrointestinal tract and uterus, usual symptoms are the following.
The [[symptoms]] of leiomyosarcoma depend on the location of the tumor. For the tumors always develop in [[gastrointestinal tract]] and [[uterus]], usual symptoms are the following.<ref name="pmid23163522">Zhang BH, Zhang HT, Wang YG (2014) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=23163522 Esophageal leiomyosarcoma: clinical analysis and surgical treatment of 12 cases.] ''Dis Esophagus'' 27 (6):547-51. [http://dx.doi.org/10.1111/j.1442-2050.2012.01444.x DOI:10.1111/j.1442-2050.2012.01444.x] PMID: [https://pubmed.gov/23163522 23163522]</ref><ref name="pmid1439022">Hartman DS, Hayes WS, Choyke PL, Tibbetts GP (1992) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=1439022 From the archives of the AFIP. Leiomyosarcoma of the retroperitoneum and inferior vena cava: radiologic-pathologic correlation.] ''Radiographics'' 12 (6):1203-20. [http://dx.doi.org/10.1148/radiographics.12.6.1439022 DOI:10.1148/radiographics.12.6.1439022] PMID: [https://pubmed.gov/1439022 1439022]</ref><ref name="pmid27530097">Jideh B, Yang T, Turner I (2017) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=27530097 Rectal Bleeding Due to Leiomyosarcoma.] ''Clin Gastroenterol Hepatol'' 15 (1):e1-e2. [http://dx.doi.org/10.1016/j.cgh.2016.08.008 DOI:10.1016/j.cgh.2016.08.008] PMID: [https://pubmed.gov/27530097 27530097]</ref><ref name="pmid11783345">Liao Q, Wang J, Han J (2001) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=11783345 [Clinical and pathological analysis on 106 cases with uterine sarcoma].] ''Zhonghua Fu Chan Ke Za Zhi'' 36 (2):104-7. PMID: [https://pubmed.gov/11783345 11783345]</ref><ref name="SahliKhmou2016">{{cite journal|last1=Sahli|first1=N.|last2=Khmou|first2=M.|last3=Khalil|first3=J.|last4=Elmajjaoui|first4=S.|last5=El Khannoussi|first5=B.|last6=Kebdani|first6=T.|last7=Elkacemi|first7=H.|last8=Benjaafar|first8=N.|title=Unusual evolution of leiomyosarcoma of the rectum: a case report and review of the literature|journal=Journal of Medical Case Reports|volume=10|issue=1|year=2016|issn=1752-1947|doi=10.1186/s13256-016-1047-8}}</ref>
* Irregular [[vaginal bleeding]] (intermenstrual or [[postmenopausal]])


*A new lump or a lump that is growing anywhere on your body<ref name="pmid7742513">Quade BJ (1995) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=7742513 Pathology, cytogenetics and molecular biology of uterine leiomyomas and other smooth muscle lesions.] ''Curr Opin Obstet Gynecol'' 7 (1):35-42. PMID: [https://pubmed.gov/7742513 7742513]</ref><ref name="pmid1439022">Hartman DS, Hayes WS, Choyke PL, Tibbetts GP (1992) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=1439022 From the archives of the AFIP. Leiomyosarcoma of the retroperitoneum and inferior vena cava: radiologic-pathologic correlation.] ''Radiographics'' 12 (6):1203-20. [http://dx.doi.org/10.1148/radiographics.12.6.1439022 DOI:10.1148/radiographics.12.6.1439022] PMID: [https://pubmed.gov/1439022 1439022]</ref>
*A new [[lump]] or a [[mass]] that is protruding into [[vagina]] or growing mass in [[abdomen]] or [[pelvis]]


*[[Abdominal pain]] in Uterine Leiomyosarcoma
*[[Abdominal pain]] in [[uterine]] leiomyosarcoma


*[[Pelvic pain]] in Uterine Leiomyosarcoma
*[[Pelvic pain]] in uterine leiomyosarcoma
*Dysphagia in Esophageal Leiomyosarcoma<ref name="pmid23163522">Zhang BH, Zhang HT, Wang YG (2014) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=23163522 Esophageal leiomyosarcoma: clinical analysis and surgical treatment of 12 cases.] ''Dis Esophagus'' 27 (6):547-51. [http://dx.doi.org/10.1111/j.1442-2050.2012.01444.x DOI:10.1111/j.1442-2050.2012.01444.x] PMID: [https://pubmed.gov/23163522 23163522]</ref>
*[[Dysphagia]] in esophageal leiomyosarcoma
    
    
*[[Hematemesis]] in Esophageal Leiomyosarcoma
*[[Hematemesis]] in [[esophageal]] leiomyosarcoma


*Black, tarry stools or rectal bleeding<ref name="pmid27530097">Jideh B, Yang T, Turner I (2017) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=27530097 Rectal Bleeding Due to Leiomyosarcoma.] ''Clin Gastroenterol Hepatol'' 15 (1):e1-e2. [http://dx.doi.org/10.1016/j.cgh.2016.08.008 DOI:10.1016/j.cgh.2016.08.008] PMID: [https://pubmed.gov/27530097 27530097]</ref>
*Black, [[tarry stools]] or [[rectal bleeding]] in [[rectal]] leiomyosarcoma
 
*Unusual vaginal bleeding in case of Uterine Leiomyosarcoma<ref name="pmid11783345">Liao Q, Wang J, Han J (2001) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=11783345 [Clinical and pathological analysis on 106 cases with uterine sarcoma].] ''Zhonghua Fu Chan Ke Za Zhi'' 36 (2):104-7. PMID: [https://pubmed.gov/11783345 11783345]</ref>


==References==
==References==

Latest revision as of 15:55, 2 April 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Nima Nasiri, M.D.[2]

Overview

The majority of patients with leiomyosarcoma remain asymptomatic for decades. General symptoms associated with cancer may occur including fatigue, fever, weight loss, nausea and vomiting, vaginal bleeding, vaginal discharge, feeling of pressure in abdomen or pelvic, painless growing lump in abdomen or pelvic cavity.

History and Symptoms

The symptoms of leiomyosarcoma depend on the location of the tumor. For the tumors always develop in gastrointestinal tract and uterus, usual symptoms are the following.[1][2][3][4][5]

References

  1. Zhang BH, Zhang HT, Wang YG (2014) Esophageal leiomyosarcoma: clinical analysis and surgical treatment of 12 cases. Dis Esophagus 27 (6):547-51. DOI:10.1111/j.1442-2050.2012.01444.x PMID: 23163522
  2. Hartman DS, Hayes WS, Choyke PL, Tibbetts GP (1992) From the archives of the AFIP. Leiomyosarcoma of the retroperitoneum and inferior vena cava: radiologic-pathologic correlation. Radiographics 12 (6):1203-20. DOI:10.1148/radiographics.12.6.1439022 PMID: 1439022
  3. Jideh B, Yang T, Turner I (2017) Rectal Bleeding Due to Leiomyosarcoma. Clin Gastroenterol Hepatol 15 (1):e1-e2. DOI:10.1016/j.cgh.2016.08.008 PMID: 27530097
  4. Liao Q, Wang J, Han J (2001) [Clinical and pathological analysis on 106 cases with uterine sarcoma.] Zhonghua Fu Chan Ke Za Zhi 36 (2):104-7. PMID: 11783345
  5. Sahli, N.; Khmou, M.; Khalil, J.; Elmajjaoui, S.; El Khannoussi, B.; Kebdani, T.; Elkacemi, H.; Benjaafar, N. (2016). "Unusual evolution of leiomyosarcoma of the rectum: a case report and review of the literature". Journal of Medical Case Reports. 10 (1). doi:10.1186/s13256-016-1047-8. ISSN 1752-1947.


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