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{{Tick-borne encephalitis}}
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{{Tick-borne encephalitis}}


==Overview==
==Overview==
There are three distinct subtypes associated with the tick-borne encephalitis virus. They include a Siberian, a Far Eastern, and a European subtype. Each subtype infection will display with different clinical manifestations. Identifying the subtype responsible for infection may assist in predicting the overall severity of the disease. Siberian may persist as a [[Chronic (medicine)|chronic]] illness, with a majority of cases resulting in [[meningeal]] forms. Far eastern, however, is more common in [[Encephalitis overview|encephalitic]] forms and European is commonly biphasic.


==Classification==
==Classification==
*TBE virus has three subtypes:
*TBE virus has three subtypes:<ref name="Sym CDC">Signs and Symptoms Centers for Disease Control and Prevention. http://www.cdc.gov/vhf/tbe/symptoms/index.html Accessed February 9, 2016 </ref>
#European subtype (Tick vector: Ixodes ricinus)
#Far Eastern subtype (Tick vector: Ixodes persulcatus)
#Siberian subtype (Tick vector: unknown)
#Siberian subtype (Tick vector: unknown)
#Far Eastern subtype (Tick vector: [[Ixodes]] persulcatus)
#European subtype (Tick vector: [[Ixodes]] ricinus)


*Subtypes may be useful in predicting the severity of infection.
*Subtypes may be useful in predicting the severity of infection.
*The following expresses the three major and most common subtypes responsible for human infection, as well as the associated symptoms.
{| style="font-size: 85%;"
! style="width: 80px; background: #4479BA; text-align: center;" |{{fontcolor|#FFF|Subtype}}
! style="width: 720px; background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Clinical manifestations}}
|-
| style="background: #F5F5F5; padding: 5px; text-align: center;" | ''Siberian''<ref name="Enceph Prime">Tick-borne Encephalitis Virus: A General Overview. http://cdn.intechopen.com/pdfs-wm/20866.pdf. Accessed February 4, 2016. </ref>
| style="background: #DCDCDC; padding: 5px;" |
*May persist as a [[chronic]] disease. 
*Less [[Encephalitis overview|focal encephalitic]] forms
*Majority of cases present in [[meningeal]] forms
*May present itself as [[biphasic]].
|-
| style="background: #F5F5F5; padding: 5px; text-align: center;" | ''Far Eastern''<ref name="Enceph Prime">Tick-borne Encephalitis Virus: A General Overview. http://cdn.intechopen.com/pdfs-wm/20866.pdf. Accessed February 4, 2016. </ref>
| style="background: #DCDCDC; padding: 5px;" |
*Commonly present in focal [[ encephalitis| encephalitic]] forms.
*Less [[meningeal]] forms
*Rarely in [[biphasic]] form
|-
| style="background: #F5F5F5; padding: 5px; text-align: center;" | ''European''<ref name="Enceph Prime">Tick-borne Encephalitis Virus: A General Overview. http://cdn.intechopen.com/pdfs-wm/20866.pdf. Accessed February 4, 2016. </ref>
| style="background: #DCDCDC; padding: 5px;" |
*Commonly a [[biphasic]] illness.
*Clinical characteristic features of the second stage include [[meningitis]], [[meningoencephalitis]], [[meningoencephalomyelitis]], and [[meningoencephaloradiculitis]].
|}
==References==
{{Reflist|2}}

Latest revision as of 18:56, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ilan Dock, B.S.

Overview

There are three distinct subtypes associated with the tick-borne encephalitis virus. They include a Siberian, a Far Eastern, and a European subtype. Each subtype infection will display with different clinical manifestations. Identifying the subtype responsible for infection may assist in predicting the overall severity of the disease. Siberian may persist as a chronic illness, with a majority of cases resulting in meningeal forms. Far eastern, however, is more common in encephalitic forms and European is commonly biphasic.

Classification

  • TBE virus has three subtypes:[1]
  1. Siberian subtype (Tick vector: unknown)
  2. Far Eastern subtype (Tick vector: Ixodes persulcatus)
  3. European subtype (Tick vector: Ixodes ricinus)
  • Subtypes may be useful in predicting the severity of infection.
  • The following expresses the three major and most common subtypes responsible for human infection, as well as the associated symptoms.
Subtype Clinical manifestations
Siberian[2]
Far Eastern[2]
European[2]

References

  1. Signs and Symptoms Centers for Disease Control and Prevention. http://www.cdc.gov/vhf/tbe/symptoms/index.html Accessed February 9, 2016
  2. 2.0 2.1 2.2 Tick-borne Encephalitis Virus: A General Overview. http://cdn.intechopen.com/pdfs-wm/20866.pdf. Accessed February 4, 2016.