Zenker's diverticulum history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ajay Gade MD[2]]

Overview

While it may be asymptomatic, Zenker's diverticulum often causes clinical manifestations such as dysphagia, globus sensation, regurgitation, cough, halitosis,odynophagia.

History and Symptoms

History

Obtaining history gives important information in making a diagnosis of ZD. It provides an insight into the cause, precipitating factors, and associated comorbid conditions. A complete history will help determine the correct therapy and helps in determining the prognosis. The areas of focus should be on onset, duration, and progression of symptoms such as:[1][2][3]

Symptoms

While it may be asymptomatic, Zenker diverticulum often causes clinical manifestations such as the following:[4][5][6][7][8][9]

Common symptoms

  • Dysphagia
  • Local pain
  • Food regurgitation
  • Halitosis
  • Coughing
  • Hoarseness
  • Aspiration pneumonia
  • Bronchitis

Less common symptoms

  • Pill dysphagia- pills stuck in the throat
  • Drooling of the saliva
  • Choking on the food
  • Globus sensation
  • Weight loss
  • Cervical borborygmi
  • Hemoptysis
  • Hematemesis

References

  1. Hoffman RM, Jaffe PE (1995). "Plummer-Vinson syndrome. A case report and literature review". Arch. Intern. Med. 155 (18): 2008–11. PMID 7575056.
  2. Mansell NJ, Jani P, Bailey CM (1999). "Plummer-Vinson syndrome--a rare presentation in a child". J Laryngol Otol. 113 (5): 475–6. PMID 10505167.
  3. Anthony R, Sood S, Strachan DR, Fenwick JD (1999). "A case of Plummer-Vinson syndrome in childhood". J. Pediatr. Surg. 34 (10): 1570–2. PMID 10549778.
  4. Hussain T, Maurer JT, Lang S, Stuck BA (2017). "[Pathophysiology, diagnosis and treatment of Zenker's diverticulum]". HNO (in German). 65 (2): 167–176. doi:10.1007/s00106-016-0302-z. PMID 27933354.
  5. Stankiewicz C (2006). "[Hypopharyngeal Zenker's diverticulum as a clinical and surgical problem]". Otolaryngol Pol (in Polish). 60 (3): 295–303. PMID 16989439.
  6. Ferreira LE, Simmons DT, Baron TH (2008). "Zenker's diverticula: pathophysiology, clinical presentation, and flexible endoscopic management". Dis. Esophagus. 21 (1): 1–8. doi:10.1111/j.1442-2050.2007.00795.x. PMID 18197932.
  7. Law R, Katzka DA, Baron TH (2014). "Zenker's Diverticulum". Clin. Gastroenterol. Hepatol. 12 (11): 1773–82, quiz e111–2. doi:10.1016/j.cgh.2013.09.016. PMID 24055983.
  8. Elbalal M, Mohamed AB, Hamdoun A, Yassin K, Miskeen E, Alla OK (2014). "Zenker's diverticulum: a case report and literature review". Pan Afr Med J. 17: 267. doi:10.11604/pamj.2014.17.267.4173. PMC 4191700. PMID 25309667.
  9. Al-Juboori AN, Al-Essawi SH (2013). "Zenker's diverticulum. A rare cause of dysphagia". Saudi Med J. 34 (1): 91–3. PMID 23299166.

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