ZHX1

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VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Zinc fingers and homeoboxes protein 1 is a protein that in humans is encoded by the ZHX1 gene.[1][2]

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants encoding the same protein.[2]

Interactions

ZHX1 has been shown to interact with NFYA.[1][3]

References

  1. 1.0 1.1 Yamada K, Printz RL, Osawa H, Granner DK (Sep 1999). "Human ZHX1: cloning, chromosomal location, and interaction with transcription factor NF-Y". Biochem Biophys Res Commun. 261 (3): 614–21. doi:10.1006/bbrc.1999.1087. PMID 10441475.
  2. 2.0 2.1 "Entrez Gene: ZHX1 zinc fingers and homeoboxes 1".
  3. Yamada, K; Osawa H; Granner D K (Oct 1999). "Identification of proteins that interact with NF-YA". FEBS Lett. NETHERLANDS. 460 (1): 41–5. doi:10.1016/S0014-5793(99)01311-3. ISSN 0014-5793. PMID 10571058.

Further reading