Wernicke-Korsakoff syndrome natural history, complications and prognosis

Wernicke-Korsakoff Syndrome Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Aditya Govindavarjhulla, M.B.B.S. [3]

Complications

• Alcohol withdrawal
• Difficulty with personal or social interaction
• Injury caused by falls
• Permanent alcoholic neuropathy
• Permanent loss of thinking skills
• Permanent loss of memory
• Shortened life span

Prognosis

• Without treatment, Wernicke-Korsakoff syndrome gets steadily worse and can be life threatening.
• With treatment, symptoms can be controlled (such as uncoordinated movement and vision difficulties) from getting worse.
• Some symptoms, especially the loss of memory and thinking skills, may be permanent. Other disorders related to alcohol abuse may also occur.